Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,801 questions · 4,079 findings · 473 reviews

No studies found 669 · 16.4%GRADE not reported 852 · 20.9%Very low 738 · 18.1%Low 903 · 22.1%Moderate 716 · 17.6%High 201 · 4.9%

Calcium hydroxide cement (Dycal) vs Calcium sulphate hemihydrate (DentoGen)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether calcium hydroxide cement (Dycal) changes radiological failure compared with calcium sulphate hemihydrate (DentoGen) (very low certainty).

1 finding from 1 review

Biodentine vs Propolis

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Biodentine showed no clear difference in clinical failure compared with propolis; GRADE not reported.

1 finding from 1 review

Vitapex (calcium hydroxide/iodoform) vs Sealapex (eugenol-free calcium hydroxide)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with sealapex (eugenol-free calcium hydroxide); GRADE not reported.

1 finding from 1 review

Non-rinse conditioner + acetone-based total-etch adhesive vs Acetone-based total-etch adhesive

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether non-rinse conditioner + acetone-based total-etch adhesive changes radiological failure compared with acetone-based total-etch adhesive (very low certainty).

1 finding from 1 review

Non‐invasive ventilation vs usual care

All‐cause mortality · Patients admitted to hospital with acute hypercapnic respiratory failure due to an exacerbation of chronic obstructive pulmonary disease…

Non‐invasive ventilation probably leads to lower mortality compared with usual medical care (moderate certainty).

1 finding from 1 review

Non‐invasive ventilation vs usual care

Need for intubation · Patients admitted to hospital with acute hypercapnic respiratory failure due to an exacerbation of chronic obstructive pulmonary disease…

Non‐invasive ventilation probably leads to lower need for endotracheal intubation compared with usual medical care (moderate certainty).

1 finding from 1 review

Intervention not reported

Failure: second attempt required · Children with pulled elbow1

The intervention may leads to lower failure: second attempt required (low certainty).

1 finding from 1 review

Intervention not reported

Failure: continued failure after second attempt using same procedure as before · Children with pulled elbow1

It is very uncertain whether the intervention changes failure: continued failure after second attempt using same procedure… (very low certainty).

1 finding from 1 review