Relief of pain · Adults over 18 years presenting with a single tooth with a clinical diagnosis of irreversible pulpitis
The review found no eligible studies for this question.
1 finding from 1 review
Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)
Activator functional appliance showed no clear difference in final overjet compared with prefabricated functional myobrace appliance (PFA); GRADE not reported.
1 finding from 1 review
Caries and/or fillings in adjacent teeth · Children aged 5 to 15 years with a compromised first permanent molar
One study found fewer decayed or filled proximal surfaces but more decayed or filled occlusal surfaces in arches with an extracted first permanent molar; ungraded.
1 finding from 1 review
Plaque · Adults (18 years or older) needing replacement of one premolar or incisor with a cantilevered fixed dental prosthesis
Metal-free cantilevered FDPs (feldspathic-veneered zirconia) showed no clear difference in plaque index (PI) compared with metal-ceramic cantilevered FDPs; GRADE not reported.
1 finding from 1 review
Crown failure · Adults (18 years or older) needing a single crown in the molar or premolar region
It is very uncertain whether metal-free single crowns (full-contour zirconia) changes crown failure compared with cast gold (conventional metal) single crowns (very low certainty).
2 findings from 1 review
Cantilevered bridge failure · Adults (18 years or older) needing replacement of one premolar or incisor with a cantilevered fixed dental prosthesis
1 finding from 1 review
Gingival index (GI) · Adults (18 years or older) needing replacement of one premolar or incisor with a cantilevered fixed dental prosthesis
Metal-free cantilevered FDPs (feldspathic-veneered zirconia) showed no clear difference in gingival index (GI) compared with metal-ceramic cantilevered FDPs; GRADE not reported.
1 finding from 1 review
Cantilevered bridge complications · Adults (18 years or older) needing replacement of one premolar or incisor with a cantilevered fixed dental prosthesis
It is very uncertain whether metal-free cantilevered FDPs (feldspathic-veneered zirconia) changes cantilevered bridge complications compared with metal-ceramic cantilevered FDPs (very low certainty).
2 findings from 1 review
Crown complications · Adults (18 years or older) needing a single crown in the molar or premolar region
It is very uncertain whether metal-free single crowns (full-contour zirconia) changes crown complications compared with cast gold (conventional metal) single crowns (very low certainty).
2 findings from 1 review
Aesthetics · Adults (18 years or older) needing a single crown in the molar or premolar region
The review found no eligible studies for this question.
1 finding from 1 review
Periodontal/peri-implant status and occlusal wear (secondary outcomes) · Adults (18 years or older) needing a single crown in the molar or premolar region
The review found no eligible studies for this question.
1 finding from 1 review
Aesthetics evaluated by the patient · Adults (18 years or older) needing replacement of one premolar or incisor with a cantilevered fixed dental prosthesis
It is very uncertain whether metal-free cantilevered FDPs (feldspathic-veneered zirconia) changes aesthetic evaluation (patient VAS) compared with metal-ceramic cantilevered FDPs (very low certainty).
1 finding from 1 review
Repositioning of ankylosed teeth after osteotomy followed or not by distraction osteogenesis, or after luxation vs Conventional orthodontic treatment or follow-up with no specific treatment for ankylosis
Outcome not reported · Any patient with ankylosis and displacement of permanent front teeth diagnosed by clinical and radiographic assessment, with or without…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Transplantation of other teeth after extraction of the ankylosed teeth vs Conventional orthodontic treatment or follow-up with no specific treatment for ankylosis
Outcome not reported · Any patient with ankylosis and displacement of permanent front teeth diagnosed by clinical and radiographic assessment, with or without…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Implant-supported crowns after extraction or decoronation of the ankylosed teeth vs Conventional orthodontic treatment or follow-up with no specific treatment for ankylosis
Outcome not reported · Any patient with ankylosis and displacement of permanent front teeth diagnosed by clinical and radiographic assessment, with or without…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Small‐for‐gestational age · pregnant women and their infants..
Meta-analysis of observational studies (higher vs lower maternal 25(OH)D) for Small for gestational age: OR 0.54 (95% CI 0.44 to 0.67), statistically significant. Umbrella review outcome-level evidence grade: Suggestive.
1 finding from 1 review
Head circumference (mm) · pregnant women and their infants..
Meta-analysis of observational studies (higher vs lower maternal 25(OH)D) for Head circumference: WMD 0.05 (95% CI -0.24 to 0.34), not statistically significant. Umbrella review outcome-level evidence grade: Suggestive.
1 finding from 1 review
Gestational age at birth (weeks) · pregnant women
Meta-analysis of randomised trials of vitamin D supplementation for Mean gestational age at delivery: WMD 0.17 (95% CI -0.16 to 0.51), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
1 finding from 1 review
WMD 0.17 [-0.16, 0.51]
2 studies
GRADE not reported
Birth length · pregnant women and their infants..
Meta-analysis of observational studies (higher vs lower maternal 25(OH)D) for Birth length: WMD 0.19 (95% CI -0.26 to 0.65), not statistically significant. Umbrella review outcome-level evidence grade: Substantial effect unlikely.
1 finding from 1 review
Small‐for‐gestational age · pregnant women
Meta-analysis of randomised trials of vitamin D supplementation for Small for gestational age: RR 0.67 (95% CI 0.40 to 1.11), not statistically significant. Umbrella review outcome-level evidence grade: Suggestive.
1 finding from 1 review