Findings

What do systematic reviews say?

4,815 questions · 6,211 findings · 638 reviews · Headline outcomes only

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No studies found 1,052 · 16.9%GRADE not reported 441 · 7.1%Very low 1,700 · 27.4%Low 1,651 · 26.6%Moderate 1,070 · 17.2%High 297 · 4.8%

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Helium thermal coagulator vs electrodiathermy

Quality of life (9 months) – EHP‐30 control and powerlessness · endometriosis

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 119 participants
Very low

Helium thermal coagulator vs electrodiathermy

Quality of life (emotional) · endometriosis

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 119 participants
Very low

Helium thermal coagulator vs electrodiathermy

Quality of life (9 months) – EHP‐30 social support · endometriosis

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 119 participants
Very low

Helium thermal coagulator vs electrodiathermy

Quality of life (9 months) – EHP‐30 self‐image · endometriosis

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 119 participants
Very low

Helium thermal coagulator vs electrodiathermy

Adverse events · endometriosis

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 192 participants
Very low

Laparoscopic treatment vs diagnostic laparoscopy

Overall pain scores unclear measurement instrument (12 months) · women with endometriosis

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
Very low

Laparoscopic treatment vs diagnostic laparoscopy

Live birth · women with endometriosis

The review found no eligible studies for this question.

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Laparoscopic treatment vs diagnostic laparoscopy

Quality of life EQ‐5D index summary (6 months) · women with endometriosis

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low

Laparoscopic treatment vs diagnostic laparoscopy

Health‐related quality of life (mental) · women with endometriosis

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low

Laparoscopic treatment vs diagnostic laparoscopy

Health‐related quality of life (physical) · women with endometriosis

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low

Laparoscopic treatment vs diagnostic laparoscopy

Viable intrauterine Pregnancy · women with endometriosis

Laparoscopic treatment probably leads to higher viable intrauterine pregnancy confirmed by ultrasound compared with diagnostic laparoscopy (moderate certainty).

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
OR 1.89 [1.25, 2.86]
3 studies · 528 participants
Moderate

Laparoscopic treatment vs diagnostic laparoscopy

Pregnancy loss: ectopic pregnancy per pregnancy · women with endometriosis

Laparoscopic treatment showed no clear difference in pregnancy loss: ectopic pregnancy per pregnancy compared with diagnostic laparoscopy (low certainty).

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
OR 1.18 [0.1, 13.48]
1 study · 100 participants
Low

Laparoscopic treatment vs diagnostic laparoscopy

Miscarriage pregnancy rate · women with endometriosis

Laparoscopic treatment showed no clear difference in pregnancy loss: miscarriage per pregnancy compared with diagnostic laparoscopy (low certainty).

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
OR 0.94 [0.35, 2.54]
2 studies · 112 participants
Low

LNG‐IUS vs non‐intrauterine progestogen

Regression of EH; by length of · endometrial hyperplasia

LNG‐IUS probably leads to higher regression of EH; by length of compared with non‐intrauterine progestogen (moderate certainty).

2 findings from 1 review

Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia 2020 · Cochrane Headline outcomes only
OR 2.94 [2.1, 4.13]
10 studies · 1108 participants
Moderate
Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia 2020 · Cochrane Headline outcomes only
OR 3.8 [1.75, 8.23]
1 study · 138 participants
Low

LNG vs no treatment

Adverse effects associated with hormones · women with endometrial hyperplasia

The review found no eligible studies for this question.

1 finding from 1 review

Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

LNG vs no treatment

Adverse effects requiring withdrawal/discontinuation of study medication · women with endometrial hyperplasia

The review found no eligible studies for this question.

1 finding from 1 review

Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

LNG vs no treatment

Satisfaction · women with endometrial hyperplasia

The review found no eligible studies for this question.

1 finding from 1 review

Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

LNG vs no treatment

Costs · women with endometrial hyperplasia

The review found no eligible studies for this question.

1 finding from 1 review

Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

LNG‐IUS vs non‐intrauterine progestogen

Hysterectomy; histologically and non‐histologically indicated · endometrial hyperplasia

LNG‐IUS may leads to lower hysterectomy; histologically and non‐histologically indicated compared with non‐intrauterine progestogen (low certainty).

1 finding from 1 review

Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia 2020 · Cochrane Headline outcomes only
OR 0.26 [0.15, 0.46]
4 studies · 452 participants
Low

LNG‐IUS vs non‐intrauterine progestogen

Adverse effects associated with hormones:Bleeding/spotting Nausea Weight gain · endometrial hyperplasia

It is very uncertain whether LNG‐IUS changes adverse effects associated with hormones:Bleeding/spotting Nausea… compared with non‐intrauterine progestogen (very low certainty).

1 finding from 1 review

Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia 2020 · Cochrane Headline outcomes only
OR 2.13 [1.33, 3.43]
3 studies · 428 participants
Very low