Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,760 questions · 8,065 findings · 1,036 reviews

No studies found 1,686 · 20.9%GRADE not reported 675 · 8.4%Very low 1,953 · 24.2%Low 2,048 · 25.4%Moderate 1,296 · 16.1%High 407 · 5%

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Facemask with rapid maxillary expansion (RME) vs Reverse Twin Block with lip pads and rapid maxillary expander (RME)

ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask with rapid maxillary expansion (RME) led to lower ANB compared with reverse Twin Block with lip pads and rapid maxillary expander (RME); GRADE not reported.

1 finding from 1 review

Facemask (RME) or modified facemask vs Surgically-anchored appliance (miniscrews or miniplates)

Perceived need for surgery in adulthood · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

The review found no eligible studies for this question.

1 finding from 1 review

Non-surgical orthodontic treatment (any: facemask, chin cup, tandem traction bow, mandibular headgear, ORTA, reverse Twin Block, Reverse Forsus) vs no treatment

ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Non-surgical orthodontic treatment (any: facemask, chin cup, tandem… probably leads to higher ANB compared with no treatment (moderate certainty).

1 finding from 1 review

Facemask with rapid maxillary expansion (RME) vs Reverse Forsus

Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask with rapid maxillary expansion (RME) showed no clear difference in overjet compared with reverse Forsus; GRADE not reported.

1 finding from 1 review

Summary of findings table ‐ Silicone earplugs vs no earplugs

Cerebral palsy · preterm or very low birth weight infants

It is very uncertain whether summary of findings table ‐ Silicone earplugs changes cerebral palsy at 18 to 22 months' corrected age compared with no earplugs (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Silicone earplugs vs no earplugs

Normal auditory functioning at discharge · preterm or very low birth weight infants

It is very uncertain whether summary of findings table ‐ Silicone earplugs changes normal auditory functioning at discharge compared with no earplugs (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Silicone earplugs vs no earplugs

All‐cause mortality during hospital stay · preterm or very low birth weight infants

It is very uncertain whether summary of findings table ‐ Silicone earplugs changes all‐cause mortality during hospital stay compared with no earplugs (very low certainty).

1 finding from 1 review

Facemask with rapid maxillary expansion (RME) vs Facemask only

Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask with rapid maxillary expansion (RME) may leads to higher overjet compared with facemask only (low certainty).

1 finding from 1 review

Tandem traction bow appliance vs no intervention

Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Tandem traction bow appliance led to higher overjet compared with untreated control (no treatment); GRADE not reported.

1 finding from 1 review

Facemask with rapid maxillary expansion (RME) vs Reverse Forsus

ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask with rapid maxillary expansion (RME) led to higher ANB compared with reverse Forsus; GRADE not reported.

1 finding from 1 review

Facemask with rapid maxillary expansion (RME) vs Facemask only

ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask with rapid maxillary expansion (RME) showed no clear difference in ANB compared with facemask only (low certainty).

1 finding from 1 review

Facemask with rapid maxillary expansion (RME) vs Modified tandem appliance

Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask with rapid maxillary expansion (RME) led to higher overjet compared with modified tandem appliance; GRADE not reported.

1 finding from 1 review

Facemask vs no intervention

Adverse effects (temporomandibular joint signs and symptoms) · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
1 finding from 1 review

Facemask after Alt-RAMEC vs Facemask started simultaneously with Alt-RAMEC

Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask after Alt-RAMEC showed no clear difference in overjet compared with facemask started simultaneously with Alt-RAMEC; GRADE not reported.

1 finding from 1 review

Orthodontic removable traction appliance (ORTA) vs no intervention

ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Orthodontic removable traction appliance (ORTA) led to higher ANB compared with untreated control (no treatment); GRADE not reported.

1 finding from 1 review