Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

155 questions · 173 findings · 22 reviews · Heart

No studies found 32 · 18.5%GRADE not reported 1 · 0.6%Very low 38 · 22%Low 66 · 38.2%Moderate 30 · 17.3%High 6 · 3.5%

Nurse‐led titration vs usual care

Heart failure hospitalisation (RR) · people with heart failure with reduced ejection fraction

Nurse‐led titration probably leads to lower heart failure‐related hospital admissions compared with usual care (moderate certainty).

1 finding from 1 review

Nurse‐led titration vs usual care

Proportion reaching target dose of medications · people with heart failure with reduced ejection fraction

Nurse‐led titration may leads to higher proportion reaching target dose of medications compared with usual care (low certainty).

1 finding from 1 review