Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

303 questions · 322 findings · 45 reviews

No studies found 31 · 9.6%GRADE not reported 22 · 6.8%Very low 99 · 30.7%Low 95 · 29.5%Moderate 68 · 21.1%High 7 · 2.2%

Routine invasive strategies vs selective invasive strategies (conservative)

Patient readmissions · participants with UA/NSTEMI in the stent era

Routine invasive strategies probably leads to lower rehospitalisation compared with selective invasive strategies (conservative) (moderate certainty).

1 finding from 1 review

Routine invasive strategies vs selective invasive strategies (conservative)

Complications of angiography or revascularization Bleeding · participants with UA/NSTEMI in the stent era

Routine invasive strategies probably leads to higher complications of angiography or revascularization Bleeding compared with selective invasive strategies (conservative) (moderate certainty).

1 finding from 1 review

Routine invasive strategies vs selective invasive strategies (conservative)

Complications of angiography or revascularization Procedure‐related myocardial infarction · participants with UA/NSTEMI in the stent era

Routine invasive strategies probably leads to higher complications of angiography or revascularization Procedure‐related… compared with selective invasive strategies (conservative) (moderate certainty).

1 finding from 1 review

Prophylactic vs selective blood transfusion

Severe maternal morbidity (congestive cardiac failure) · patients with sickle cell disease in pregnancy

It is very uncertain whether prophylactic changes severe maternal morbidity (congestive cardiac failure) compared with selective blood transfusion (very low certainty).

1 finding from 1 review

Elective radical (comprehensive) neck dissection vs Elective selective neck dissection

Total mortality · Adults with oral cavity cancer
1 finding from 1 review

Elective radical (comprehensive) neck dissection vs Elective selective neck dissection

Adverse events associated with treatment · Adults with oral cavity cancer
1 finding from 1 review

Elective radical (comprehensive) neck dissection vs Elective selective neck dissection

Recurrence · Adults with oral cavity cancer

It is very uncertain whether elective radical (comprehensive) neck dissection changes recurrence compared with elective selective neck dissection (very low certainty).

1 finding from 1 review

Elective radical (comprehensive) neck dissection vs Elective selective neck dissection

Disease-free survival · Adults with oral cavity cancer

It is very uncertain whether elective radical (comprehensive) neck dissection changes disease-free survival (new disease, progression, and mortality) compared with elective selective neck dissection (very low certainty).

1 finding from 1 review

Sealing using sealant materials vs Selective carious tissue removal (selective excavation, SE)

Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…

It is very uncertain whether sealing using sealant materials changes failure of therapy compared with selective carious tissue removal (selective excavation, SE) (very low certainty).

1 finding from 1 review

Sealing using sealant materials vs Selective carious tissue removal (selective excavation, SE)

Lesion progression · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…
1 finding from 1 review
  • Interventions for treating cavitated or dentine carious lesions 2021 · Cochrane All outcomes
    Cavitated lesions, primary dentition
    Lesion progression reported narratively: Dias 2018 1/27 sealed vs 1/21 SE at 24 months; Hesse 2014 0/17 sealed vs 0/17 SE at 18 months; not pooled and not GRADE-rated.
    2 studies
    GRADE not reported