Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

180 questions · 181 findings · 35 reviews

No studies found 62 · 34.3%GRADE not reported 13 · 7.2%Very low 47 · 26%Low 40 · 22.1%Moderate 18 · 9.9%High 1 · 0.6%

Pharmacomechanical thrombolysis (Cragg® catheter) vs pulse spray technique

Technical success · thrombosed haemodialysis arteriovenous fistulas and grafts

It is very uncertain whether pharmacomechanical thrombolysis (Cragg® catheter) changes technical success compared with pulse spray technique (very low certainty).

1 finding from 1 review

Pharmacomechanical thrombolysis (Cragg® catheter) vs pulse spray technique

Minor adverse events · thrombosed haemodialysis arteriovenous fistulas and grafts

It is very uncertain whether pharmacomechanical thrombolysis (Cragg® catheter) changes minor adverse events compared with pulse spray technique (very low certainty).

1 finding from 1 review

Pharmacomechanical thrombolysis (Cragg® catheter) vs pulse spray technique

Major adverse events · thrombosed haemodialysis arteriovenous fistulas and grafts

It is very uncertain whether pharmacomechanical thrombolysis (Cragg® catheter) changes major adverse events compared with pulse spray technique (very low certainty).

1 finding from 1 review

Cyclosporin vs mycophenolate mofetil with pulse dexamethasone

Complete remission · idiopathic steroid‐resistant nephrotic syndrome in children

Cyclosporin showed no clear difference in treatment response at 52 weeks: complete remission (primary outcome… compared with mycophenolate mofetil with pulse dexamethasone (moderate certainty).

1 finding from 1 review

Cyclosporin vs mycophenolate mofetil with pulse dexamethasone

Partial remission ( · idiopathic steroid‐resistant nephrotic syndrome in children

Cyclosporin showed no clear difference in treatment response at 52 weeks: partial remission (primary outcome 3) compared with mycophenolate mofetil with pulse dexamethasone (moderate certainty).

1 finding from 1 review

Cyclosporin vs mycophenolate mofetil with pulse dexamethasone

Sustainable remission between 52 and 78 weeks: complete or partial remission (primary outcome 1, 2, 3) · idiopathic steroid‐resistant nephrotic syndrome in children

Cyclosporin showed no clear difference in sustainable remission between 52 and 78 weeks: complete or partial… compared with mycophenolate mofetil with pulse dexamethasone (moderate certainty).

1 finding from 1 review