Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

807 questions · 849 findings · 68 reviews · Headline outcomes only

No studies found 236 · 27.8%GRADE not reported 50 · 5.9%Very low 266 · 31.3%Low 168 · 19.8%Moderate 104 · 12.2%High 25 · 2.9%

Psychological therapy vs usual care or attention control

Depression: meeting study criteria for depression at end of · people with depression after stroke

It is very uncertain whether psychological therapy changes depression: meeting study criteria for depression at end of… compared with usual care and/or attention control (very low certainty).

1 finding from 1 review

Psychological therapy vs usual care or attention control

Adverse events: death ‐ at end of treatment (secondary outcome) · people with depression after stroke

It is very uncertain whether psychological therapy changes adverse events: death ‐ at end of treatment (secondary outcome) compared with usual care and/or attention control (very low certainty).

1 finding from 1 review

Non‐invasive brain stimulation vs usual care with or without sham interventions

Depression: meeting study criteria for depression at end of · people with depression after stroke

It is very uncertain whether non‐invasive brain stimulation changes depression: meeting study criteria for depression at end of… compared with sham non‐invasive brain stimulation and/or usual care (very low certainty).

1 finding from 1 review

Non‐invasive brain stimulation vs usual care with or without sham interventions

Depression: < 50% reduction in scale scores at end of treatment (primary outcome) · people with depression after stroke

It is very uncertain whether non‐invasive brain stimulation changes depression: < 50% reduction in scale scores at end of treatment… compared with sham non‐invasive brain stimulation and/or usual care (very low certainty).

1 finding from 1 review

Mood stabilisers vs placebo

Self‐harm Measured by: clinicians Timing of outcome assessment: end of treatment · patients with borderline personality disorder

It is very uncertain whether mood stabilisers changes self‐harm Timing of outcome assessment: end of treatment (52 weeks… compared with placebo (very low certainty).

1 finding from 1 review

Antipsychotics vs placebo

Self‐harm Measured by: clinicians Timing of outcome assessment: end of treatment · patients with borderline personality disorder

It is very uncertain whether antipsychotics changes self‐harm Timing of outcome assessment: end of treatment (8 to 24… compared with placebo (very low certainty).

1 finding from 1 review