Findings

What do systematic reviews say?

151 questions · 171 findings · 15 reviews

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No studies found 26 · 15.2%GRADE not reported 21 · 12.3%Very low 52 · 30.4%Low 49 · 28.7%Moderate 20 · 11.7%High 3 · 1.8%

Intravenous preparations vs oral preparations

Number of responders · IBD patients

Intravenous preparations may leads to higher number of responders compared with oral preparations (low certainty).

1 finding from 1 review

Interventions for treating iron deficiency anaemia in inflammatory bowel disease 2021 · Cochrane Headline outcomes only
RR 1.17 [1.05, 1.31]
5 studies · 927 participants
Low

Intravenous preparations vs oral preparations

Withdrawals due to adverse events · IBD patients

Intravenous preparations may leads to lower withdrawal due to adverse events compared with oral preparations (low certainty).

1 finding from 1 review

Interventions for treating iron deficiency anaemia in inflammatory bowel disease 2021 · Cochrane Headline outcomes only
RR 0.39 [0.2, 0.74]
5 studies · 927 participants
Low

Intervention not reported

Ferritin: final or change (µg/L) · adults and children with CKD

1 finding from 1 review

Parenteral versus oral iron therapy for adults and children with chronic kidney disease 2019 · Cochrane Headline outcomes only
no estimate extracted
33 studies · 3389 participants
Low

Intervention not reported

TSAT: final or change (%) · adults and children with CKD

1 finding from 1 review

Parenteral versus oral iron therapy for adults and children with chronic kidney disease 2019 · Cochrane Headline outcomes only
no estimate extracted
27 studies · 3089 participants
Low

Intervention not reported

HCT (%) · adults and children with CKD

1 finding from 1 review

Parenteral versus oral iron therapy for adults and children with chronic kidney disease 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 152 participants
Very low

Intervention not reported

ESA dose: final or change · adults and children with CKD

1 finding from 1 review

Parenteral versus oral iron therapy for adults and children with chronic kidney disease 2019 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 522 participants
Low

Intervention not reported

eGFR: final or change (mL/min) · adults and children with CKD

1 finding from 1 review

Parenteral versus oral iron therapy for adults and children with chronic kidney disease 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1052 participants
Low

Intervention not reported

Number achieving target Hb or increase ≥1 g/dL · adults and children with CKD

The intervention may leads to higher number achieving target Hb or increase ≥1 g/dL (low certainty).

1 finding from 1 review

Parenteral versus oral iron therapy for adults and children with chronic kidney disease 2019 · Cochrane Headline outcomes only
RR 1.71 [1.43, 2.04]
13 studies · 2206 participants
Low

Intervention not reported

Hb: final or change (g/dL) · adults and children with CKD

1 finding from 1 review

Parenteral versus oral iron therapy for adults and children with chronic kidney disease 2019 · Cochrane Headline outcomes only
no estimate extracted
31 studies · 3373 participants
Low

Intervention not reported

Subgroup · children in malaria‐endemic areas

The review found no eligible studies for this question.

1 finding from 1 review

Oral iron supplements for children in malaria‐endemic areas 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Clinical malaria Subgrouped by presence of malaria prevention or management services · children in malaria‐endemic areas

The intervention may leads to lower clinical malaria Subgrouped by presence of malaria prevention or… (low certainty).

1 finding from 1 review

Oral iron supplements for children in malaria‐endemic areas 2016 · Cochrane Headline outcomes only
RR 0.91 [0.84, 0.97]
7 studies · 5586 participants
Low