Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

204 questions · 208 findings · 37 reviews · Gynaecology and Fertility

No studies found 35 · 16.8%GRADE not reported 4 · 1.9%Very low 62 · 29.8%Low 70 · 33.7%Moderate 32 · 15.4%High 5 · 2.4%

Hyaluronic acid‐selected sperm (HA‐ICSI) vs viscous medium containing HA (SpermSlow)

Live birth rate per woman · assisted reproduction

It is very uncertain whether hyaluronic acid‐selected sperm (HA‐ICSI) changes live birth per woman randomly assigned compared with viscous medium containing HA (SpermSlow) (very low certainty).

1 finding from 1 review

Hyaluronic acid‐selected sperm (HA‐ICSI) vs viscous medium containing HA (SpermSlow)

Miscarriage per clinical pregnancy · assisted reproduction

It is very uncertain whether hyaluronic acid‐selected sperm (HA‐ICSI) changes miscarriage per clinical pregnancy compared with viscous medium containing HA (SpermSlow) (very low certainty).

1 finding from 1 review

Hyaluronic acid‐selected sperm (HA‐ICSI) vs viscous medium containing HA (SpermSlow)

Clinical pregnancy · assisted reproduction

It is very uncertain whether hyaluronic acid‐selected sperm (HA‐ICSI) changes clinical pregnancy per woman randomly assigned compared with viscous medium containing HA (SpermSlow) (very low certainty).

1 finding from 1 review

Intentional endometrial injury vs no intervention or a sham procedure

Live birth · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)

Intentional endometrial injury showed no clear difference in live birth (primary analysis) compared with no intervention or a sham procedure (low certainty).

1 finding from 1 review

Intervention not reported

Live birth or ongoing pregnancy: early (EFP) vs late (LFP) follicular phase · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Clinical pregnancy: early (EFP) vs late (LFP) follicular phase (sensitivity analysis) · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)

It is very uncertain whether the intervention changes clinical pregnancy: early (EFP) vs late (LFP) follicular phase… (very low certainty).

1 finding from 1 review

Intentional endometrial injury vs no intervention or a sham procedure

Live birth or ongoing pregnancy · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)

It is very uncertain whether intentional endometrial injury changes live birth or ongoing pregnancy (sensitivity analysis) compared with no intervention or a sham procedure (very low certainty).

1 finding from 1 review

Intentional endometrial injury vs no intervention or a sham procedure

Clinical pregnancy · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)
2 findings from 1 review