Findings

What do systematic reviews say?

148 questions · 150 findings · 29 reviews · Pain, Palliative and Supportive Care

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No studies found 22 · 14.7%GRADE not reported 19 · 12.7%Very low 68 · 45.3%Low 24 · 16%Moderate 13 · 8.7%High 4 · 2.7%

Perioperative infraorbital nerve block vs Placebo (sham/placebo device)

Need for analgesic prescription for pain (supplemental analgesic requirements) · Children up to 13 years of age, undergoing cleft lip repair surgery

Perioperative infraorbital nerve block may leads to lower need for analgesic prescription for pain (supplemental analgesic… compared with placebo (sham block) (low certainty).

1 finding from 1 review

Infraorbital nerve block for postoperative pain following cleft lip repair in children 2016 · Cochrane All outcomes
At 4 hours
RR 0.05 [0.01, 0.18]
3 studies · 120 participants
Low

Perioperative infraorbital nerve block vs Placebo (sham/placebo device)

Adverse events · Children up to 13 years of age, undergoing cleft lip repair surgery

1 finding from 1 review

Infraorbital nerve block for postoperative pain following cleft lip repair in children 2016 · Cochrane All outcomes
2 out of 3 studies reported this outcome. One study reported no differences between groups, and the other study reported more vomiting in the placebo group (Takmaz 2009: vomiting 40% placebo versus 10% intervention; P…
2 studies
GRADE not reported

Perioperative infraorbital nerve block vs Infiltration of the incision (peri-incisional infiltration)

Heart rate, respiratory rate, and blood pressure · Children up to 13 years of age, undergoing cleft lip repair surgery

1 finding from 1 review

Infraorbital nerve block for postoperative pain following cleft lip repair in children 2016 · Cochrane All outcomes
Gaonkar 2004: no differences between groups in postoperative heart rate and blood pressure. Prabhu 1999: significantly lower heart rates in the intervention group throughout the postoperative period, and no differences…
2 studies
GRADE not reported

Perioperative infraorbital nerve block vs Infiltration of the incision (peri-incisional infiltration)

Time to feeding after surgery · Children up to 13 years of age, undergoing cleft lip repair surgery

The review found no eligible studies for this question.

1 finding from 1 review

Infraorbital nerve block for postoperative pain following cleft lip repair in children 2016 · Cochrane All outcomes
This outcome was not reported.
0 studies
No studies found

Perioperative infraorbital nerve block vs Placebo (sham/placebo device)

Length of hospital stay · Children up to 13 years of age, undergoing cleft lip repair surgery

The review found no eligible studies for this question.

1 finding from 1 review

Infraorbital nerve block for postoperative pain following cleft lip repair in children 2016 · Cochrane All outcomes
None of the included studies reported this outcome.
0 studies
No studies found

Perioperative infraorbital nerve block vs Intravenous analgesia

Duration of postoperative analgesia · Children up to 13 years of age, undergoing cleft lip repair surgery

The review found no eligible studies for this question.

1 finding from 1 review

Infraorbital nerve block for postoperative pain following cleft lip repair in children 2016 · Cochrane All outcomes
This outcome was not reported.
0 studies
No studies found

Perioperative infraorbital nerve block vs Infiltration of the incision (peri-incisional infiltration)

Adverse events · Children up to 13 years of age, undergoing cleft lip repair surgery

1 finding from 1 review

Infraorbital nerve block for postoperative pain following cleft lip repair in children 2016 · Cochrane All outcomes
Of the 2 included studies, one study reported no difference between groups (Gaonkar 2004: no adverse events attributable to either technique), and the other study did not report this outcome.
1 study
GRADE not reported

Perioperative infraorbital nerve block vs Intravenous analgesia

Analgesia durationTime duration from the end of surgery to the time of first analgesic consumption. Scale from: 0 to 100. · Children up to 13 years of age, undergoing cleft lip repair surgery

1 finding from 1 review

Infraorbital nerve block for postoperative pain following cleft lip repair in children 2016 · Cochrane All outcomes
Not pooled (lack of data). Delgado 2005: longer in the infraorbital block group (7.3 +/- 5.1 hours) versus intravenous analgesia (2.8 +/- 2.2 hours) (P < 0.01). Simion 2008: no significant difference (195.32 +/- 71.21…
3 studies
GRADE not reported