Findings

What do systematic reviews say?

172 questions · 181 findings · 11 reviews

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No studies found 35 · 19.3%GRADE not reported 3 · 1.7%Very low 68 · 37.6%Low 70 · 38.7%Moderate 5 · 2.8%High 0 · 0%

Soft catheters vs Firm catheters

Instrumental assistance needed · women trying to conceive by intrauterine insemination

1 finding from 1 review

Soft versus firm catheters for intrauterine insemination 2010 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 986 participants
GRADE not reported

Soft catheters vs Firm catheters

Blood on catheter tip · women trying to conceive by intrauterine insemination

1 finding from 1 review

Soft versus firm catheters for intrauterine insemination 2010 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 852 participants
GRADE not reported

Soft catheters vs Firm catheters

Cramping · women trying to conceive by intrauterine insemination

1 finding from 1 review

Soft versus firm catheters for intrauterine insemination 2010 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 290 participants
GRADE not reported

Soft catheters vs Firm catheters

Miscarriage · women trying to conceive by intrauterine insemination

It is very uncertain whether soft catheters changes miscarriage per woman compared with firm catheters (very low certainty).

1 finding from 1 review

Soft versus firm catheters for intrauterine insemination 2010 · Cochrane Headline outcomes only
OR 1.25 [0.49, 3.22]
2 studies · 645 participants
Very low

Operative hysteroscopy vs control

Live birth · subfertile women with endometrial polyps diagnosed by ultrasonography prior to treatment with gonadotropin and intrauterine insemination

The review found no eligible studies for this question.

1 finding from 1 review

Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Operative hysteroscopy vs control

Adverse events: hysteroscopy complications · subfertile women with endometrial polyps diagnosed by ultrasonography prior to treatment with gonadotropin and intrauterine insemination

The review found no eligible studies for this question.

1 finding from 1 review

Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Operative hysteroscopy vs control

Adverse events ‐ Miscarriage · subfertile women with endometrial polyps diagnosed by ultrasonography prior to treatment with gonadotropin and intrauterine insemination

The review found no eligible studies for this question.

1 finding from 1 review

Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Progesterone vs placebo/no treatment

Clinical pregnancy rate · women with gonadotropin stimulation

Progesterone may leads to higher clinical pregnancy rate compared with placebo/no treatment (low certainty).

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
RR 1.38 [1.1, 1.74]
7 studies · 1437 participants
Low

Progesterone vs placebo/no treatment

Multiple pregnancy rate · women with gonadotropin stimulation

Progesterone showed no clear difference in multiple pregnancy rate compared with placebo/no treatment (low certainty).

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
RR 0.72 [0.17, 3.15]
1 study · 214 participants
Low

Progesterone vs placebo/no treatment

Adverse events, OHSS, preterm delivery, congenital anomaly · women with gonadotropin stimulation

The review found no eligible studies for this question.

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Progesterone vs placebo/no treatment

Live birth rate · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation

The review found no eligible studies for this question.

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Progesterone vs placebo/no treatment

Ongoing pregnancy · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation

Progesterone showed no clear difference in ongoing pregnancy rate compared with placebo/no treatment (low certainty).

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
RR 0.73 [0.37, 1.42]
1 study · 253 participants
Low

Progesterone vs placebo/no treatment

Miscarriage per clinical pregnancy · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation

Progesterone showed no clear difference in miscarriage rate per clinical pregnancy compared with placebo/no treatment (low certainty).

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
RR 0.67 [0.3, 1.5]
2 studies · 123 participants
Low

Progesterone vs placebo/no treatment

Clinical pregnancy rate · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation

Progesterone may leads to higher clinical pregnancy rate compared with placebo/no treatment (low certainty).

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
RR 1.4 [1.03, 1.9]
4 studies · 733 participants
Low

Progesterone vs placebo/no treatment

Multiple pregnancy rate · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation

Progesterone showed no clear difference in multiple pregnancy rate compared with placebo/no treatment (low certainty).

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
RR 1.44 [0.24, 8.49]
1 study · 290 participants
Low

Progesterone vs placebo/no treatment

Adverse events, OHSS, preterm delivery, congenital anomaly · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation

The review found no eligible studies for this question.

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Progesterone vs placebo/no treatment

Live birth or ongoing pregnancy · women with oral (clomiphene citrate or letrozole) stimulation

Progesterone showed no clear difference in live birth rate/ongoing pregnancy compared with placebo/no treatment (low certainty).

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
RR 0.97 [0.58, 1.64]
2 studies · 485 participants
Low

Progesterone vs placebo/no treatment

Miscarriage per clinical pregnancy · women with oral (clomiphene citrate or letrozole) stimulation

Progesterone showed no clear difference in miscarriage rate per clinical pregnancy compared with placebo/no treatment (low certainty).

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
RR 0.53 [0.25, 1.14]
2 studies · 119 participants
Low

Progesterone vs placebo/no treatment

Clinical pregnancy · women with oral (clomiphene citrate or letrozole) stimulation

Progesterone may leads to higher clinical pregnancy compared with placebo/no treatment (low certainty).

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
RR 1.44 [1.04, 1.98]
6 studies · 1073 participants
Low

Progesterone vs placebo/no treatment

Multiple pregnancy · women with oral (clomiphene citrate or letrozole) stimulation

Progesterone showed no clear difference in multiple pregnancy compared with placebo/no treatment (low certainty).

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
RR 0.58 [0.1, 3.55]
2 studies · 586 participants
Low