Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

208 questions · 245 findings · 21 reviews

No studies found 54 · 22%GRADE not reported 6 · 2.4%Very low 50 · 20.4%Low 39 · 15.9%Moderate 69 · 28.2%High 27 · 11%

BoNT‐A vs sham

Adverse events · children with CP

BoNT‐A showed no clear difference in adverse events compared with placebo or sham (moderate certainty).

3 findings from 1 review

BoNT‐A vs sham

Instrumented gait analysis (kinematics) (not measured) · children with CP

The review found no eligible studies for this question.

2 findings from 1 review

BoNT‐A vs serial casting

Instrumented gait analysis (peak ankle dorsiflexion in stance) · children with CP
3 findings from 1 review

BoNT‐A vs serial casting

Observational gait analysis · children with CP
3 findings from 1 review

BoNT‐A vs serial casting

Function · children with CP
3 findings from 1 review

BoNT‐A vs serial casting

Satisfaction (not measured) · children with CP

The review found no eligible studies for this question.

3 findings from 1 review

BoNT‐A vs serial casting

Spasticity (ankle plantarflexors) · children with CP
3 findings from 1 review

BoNT‐A vs serial casting

Adverse events · children with CP

BoNT‐A showed no clear difference in adverse events compared with serial casting (low certainty).

3 findings from 1 review

Systemic antispasticity drugs vs placebo

Indirect measure of spasticity Modified Ashworth Scale · people with spasticity following stroke

It is very uncertain whether systemic antispasticity drugs changes indirect measure of spasticity Modified Ashworth Scale compared with placebo (very low certainty).

1 finding from 1 review