Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

371 questions · 390 findings · 17 reviews · Orthodontics

No studies found 88 · 22.6%GRADE not reported 203 · 52.1%Very low 38 · 9.7%Low 38 · 9.7%Moderate 20 · 5.1%High 3 · 0.8%

Two-band palatal expander with slow expansion vs Two-band palatal expander with rapid expansion

Molar expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…
1 finding from 1 review
  • Orthodontic treatment for posterior crossbites 2021 · Cochrane All outcomes
    7 months after start of treatment
    Martina 2012: slow 6.3 mm (SD 2.1) vs rapid 5.7 mm (SD 1.6); reported as no statistically significant difference in text (PUB2 MD 0.60, 95% CI -0.85 to 2.05); Table 1 lists P<0.001 (discrepant)
    1 study · 26 participants
    GRADE not reported

Lower lip bumper vs No active treatment (control)

Amount of crowding · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

It is very uncertain whether lower lip bumper changes amount of crowding (change in mandibular incisor crowding) at 6 months compared with no active treatment (control) (very low certainty).

1 finding from 1 review

Fixed tooth-borne expansion (quad-helix) vs observation

Crossbite correction · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…

Fixed tooth-borne expansion (quad-helix) leads to higher crossbite correction compared with observation (no treatment) (high certainty).

1 finding from 1 review

Fixed tooth-borne expansion (quad-helix) vs observation

Canine expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…

Fixed tooth-borne expansion (quad-helix) may leads to higher canine expansion (inter-canine distance) compared with observation (no treatment) (low certainty).

1 finding from 1 review

Vibrational appliance with fixed appliances vs Fixed appliances

Amount of crowding · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

It is very uncertain whether vibrational appliance with fixed appliances changes amount of crowding (change in mandibular crowding) at 10 to 30 weeks compared with fixed appliances only / no vibrational appliance (control) (very low certainty).

1 finding from 1 review

Bone-borne expansion vs Fixed tooth-borne expansion (Hyrax)

Crossbite correction · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…

Bone-borne expansion showed no clear difference in crossbite correction compared with fixed tooth-borne expansion (Hyrax) (low certainty).

1 finding from 1 review

Lower lip bumper vs No active treatment (control)

Lower incisors to mandible (position, mm) at 9 months · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

Lower lip bumper led to higher lower incisors to mandible at 6 months compared with no active treatment (control); GRADE not reported.

1 finding from 1 review

Nickel-titanium archwire vs Stainless steel archwire

Amount of crowding (change in mandibular crowding) at 8 weeks · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

It is very uncertain whether nickel-titanium archwire changes amount of crowding (change in mandibular crowding) at 8 weeks compared with stainless steel archwire (very low certainty).

1 finding from 1 review

Cervical pull headgear vs Minor interceptive procedures (control)

Size of the jaws (maxillary and mandibular arch length) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

Cervical pull headgear led to higher size of the jaws (maxillary and mandibular arch length) compared with minor interceptive procedures (control); GRADE not reported.

1 finding from 1 review

Lower lip bumper vs No active treatment (control)

Size of the lower jaw (arch length) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

Lower lip bumper led to higher size of the lower jaw (mandibular arch length) at 6 months compared with no active treatment (control); GRADE not reported.

1 finding from 1 review

Fixed tooth-borne expansion (Hyrax) vs Bonded expander plate (acrylic)

Molar expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…

Fixed tooth-borne Hyrax expander showed no clear difference in molar expansion compared with bonded expander plate (acrylic); GRADE not reported.

1 finding from 1 review

Fixed bonded acrylic splint expander vs no treatment

Molar expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…

Fixed bonded acrylic splint expander showed no clear difference in molar expansion (maxillary intermolar width) compared with no treatment; GRADE not reported.

1 finding from 1 review

Glass ionomer cement (for bracket bonding) vs Resin adhesive

Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances

There is no clear difference in WSL initiation between glass ionomer cement and resin adhesive for bracket bonding (RR 0.72, not significant); certainty of evidence is very low.

1 finding from 1 review

Nickel-titanium archwire vs Multistranded stainless steel archwire

Harms (pain) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
1 finding from 1 review
  • Orthodontic treatment for crowded teeth in children 2021 · Cochrane All outcomes
    first days
    No difference in overall pain, but more pain with nickel-titanium at 12 hours and day 1 (morning, afternoon, bedtime) vs multistranded stainless steel (Sandhu 2013). Narrative; no pooled estimate.
    1 study
    GRADE not reported