Findings
What do systematic reviews say? 4,734 questions · 15,288 findings · 893 reviews
No studies found 3,864 · 25.3% GRADE not reported 2,222 · 14.5% Very low 3,868 · 25.3% Low 3,280 · 21.5% Moderate 1,676 · 11% High 378 · 2.5%
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Health‐related quality of life Mean AcroQoL score (0‐100) · adults with growth‐hormone secreting pituitary adenomas
Surgery alone showed no clear difference in health‐related quality of life Mean AcroQoL score (0‐100) compared with pharmacological therapy alone (low certainty).
1 finding from 1 review
Disease‐related complications Intubation difficulties requiring postponement of surgery · adults with growth‐hormone secreting pituitary adenomas
It is very uncertain whether surgery alone changes disease‐related complications Intubation difficulties requiring… compared with preoperative pharmacological therapy and surgery (very low certainty).
1 finding from 1 review
Recurrence · adults with growth‐hormone secreting pituitary adenomas
1 finding from 1 review
Moderate to vigorous physical activity (minutes/d) [ · adults
1 finding from 1 review
Self‐efficacy (for physical activity) (SEPA, score · adults
1 finding from 1 review
General well‐being · adults
1 finding from 1 review
Energy intake · adults
1 finding from 1 review
Adherence to Mediterranean diet (AMD) score change (score · adults
1 finding from 1 review
Healthy eating index (HEI‐2005) score change (score · adults
1 finding from 1 review
Adverse events · adults
1 finding from 1 review
Estimated energy expenditure (EEE) (min/week) · adults
1 finding from 1 review
Leisure time physical activity (LTPA)(kcal/week) · adults
1 finding from 1 review
Cardiorespiratory fitness (CF) (mL/kg/min) · adults
1 finding from 1 review
Total activity time (TAA) (min/week) · adults
1 finding from 1 review
Body‐mass index (BMI) · adults
1 finding from 1 review
Weight (kg) · adults
1 finding from 1 review
Change in weight (kg) · adults
1 finding from 1 review
Health‐related quality of life(WHOQOL‐BREF questionnaire, score · adults
1 finding from 1 review
Severity of PTSD symptoms ‐ Clinician‐rated · adults experiencing acute traumatic stress symptoms
1 finding from 1 review
Quality of life at 3 months · adults experiencing acute traumatic stress symptoms
1 finding from 1 review
evidence gaps · evidencegaps.com
Not clinical guidance. Data from the Cochrane Library (Summary of Findings tables and full text), PubMed and Crossref, extracted by the Evidence Gaps pipeline. Related-question groupings and the gap map key are proposals pending human validation. A review that found no studies, or no review at all, is not proof that no research exists.