Ketogenic diet (KD) vs other KDs
Seizure freedom · adults (aged 18 years and over) with drug‐resistant epilepsy
1 finding from 1 review
- no estimate extracted1 study · 80 participantsVery low
Findings
What do systematic reviews say?
2,805 questions · 2,912 findings · 307 reviews · Headline outcomes only
No studies found 706 · 24.2%GRADE not reported 133 · 4.6%Very low 786 · 27%Low 696 · 23.9%Moderate 474 · 16.3%High 117 · 4%
Ketogenic diet (KD) vs usual care
50% or greater reduction in seizure frequency · children (aged 1 to 18 years) with drug‐resistant epilepsy
1 finding from 1 review
- 5.8 [3.48, 9.65]4 studies · 385 participantsLow
Ketogenic diet (KD) vs other KDs
50% or greater reduction in seizure frequency · adults (aged 18 years and over) with drug‐resistant epilepsy
1 finding from 1 review
- no estimate extracted1 study · 80 participantsVery low
Ketogenic diet (KD) vs other KDs
Adverse effects · adults (aged 18 years and over) with drug‐resistant epilepsy
1 finding from 1 review
- no estimate extracted1 study · 80 participantsVery low
Ketogenic diet (KD) vs other KDs
Cognition and behaviour · adults (aged 18 years and over) with drug‐resistant epilepsy
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Ketogenic diet (KD) vs other KDs
Quality of life · adults (aged 18 years and over) with drug‐resistant epilepsy
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Ketogenic diet (KD) vs other KDs
Attrition rate · adults (aged 18 years and over) with drug‐resistant epilepsy
1 finding from 1 review
- no estimate extracted1 study · 80 participantsVery low
Ketogenic diet (KD) vs usual care
Adverse effects · children (aged 1 to 18 years) with drug‐resistant epilepsy
1 finding from 1 review
- no estimate extracted5 studies · 425 participantsLow
Ketogenic diet (KD) vs usual care
Cognition and behaviour · children (aged 1 to 18 years) with drug‐resistant epilepsy
1 finding from 1 review
- no estimate extracted1 study · 57 participantsVery low
Ketogenic diet (KD) vs usual care
Quality of life · children (aged 1 to 18 years) with drug‐resistant epilepsy
It is very uncertain whether ketogenic diet (KD) changes quality of life compared with usual care (very low certainty).
1 finding from 1 review
- OR 161 study · 57 participantsVery low
Ketogenic diet (KD) vs usual care
Treatment withdrawal · children (aged 1 to 18 years) with drug‐resistant epilepsy
Ketogenic diet (KD) showed no clear difference in treatment withdrawal compared with usual care (low certainty).
1 finding from 1 review
- RR 1.08 [0.74, 1.57]5 studies · 425 participantsLow
Ketogenic diet (KD) vs usual care
Seizure freedom · adults (aged 16 years and over) with drug‐resistant epilepsy
It is very uncertain whether ketogenic diet (KD) changes seizure freedom compared with usual care (very low certainty).
1 finding from 1 review
- no estimate extracted2 studies · 141 participantsVery low
Ketogenic diet (KD) vs usual care
50% or greater reduction in seizure frequency · adults (aged 16 years and over) with drug‐resistant epilepsy
It is very uncertain whether ketogenic diet (KD) changes 50% or greater reduction in seizure frequency compared with usual care (very low certainty).
1 finding from 1 review
- RR 5.03 [0.26, 97.68]2 studies · 141 participantsVery low
Ketogenic diet (KD) vs usual care
Adverse effects · adults (aged 16 years and over) with drug‐resistant epilepsy
1 finding from 1 review
- no estimate extracted2 studies · 141 participantsVery low
Green tea extract supplementation vs placebo
Prostate cancer incidence · adults (aged at least 18 years)
Green tea extract supplementation showed no clear difference in prostate cancer incidence compared with placebo (low certainty).
1 finding from 1 review
- RR 0.5 [0.18, 1.36]3 studies · 201 participantsLow
Highest vs lowest green tea exposure
Stomach cancer risk (18 studies) · adults (aged at least 18 years)
It is very uncertain whether highest changes stomach cancer risk (18 studies) compared with lowest green tea exposure (very low certainty).
1 finding from 1 review
- RR 0.86 [0.74, 1.01]438595 participantsVery low
Highest vs lowest green tea exposure
Liver cancer risk (6 studies) · adults (aged at least 18 years)
Highest showed no clear difference in liver cancer risk (6 studies) compared with lowest green tea exposure (low certainty).
1 finding from 1 review
- RR 0.88 [0.68, 1.14]198885 participantsLow
Highest vs lowest green tea exposure
Pancreatic cancer risk (9 studies) · adults (aged at least 18 years)
Highest showed no clear difference in pancreatic cancer risk (9 studies) compared with lowest green tea exposure (low certainty).
1 finding from 1 review
- RR 0.88 [0.7, 1.1]326564 participantsLow
Highest vs lowest green tea exposure
Colorectal cancer risk (16 studies) · adults (aged at least 18 years)
Highest may leads to lower colorectal cancer risk (16 studies) compared with lowest green tea exposure (low certainty).
1 finding from 1 review
- RR 0.84 [0.74, 0.96]610295 participantsLow
Highest vs lowest green tea exposure
Colon cancer risk (10 studies) · adults (aged at least 18 years)
Highest may leads to lower colon cancer risk (10 studies) compared with lowest green tea exposure (low certainty).
1 finding from 1 review
- RR 0.89 [0.8, 0.98]389974 participantsLow