What do systematic reviews say?

Summary of findings. Removable splintage vs cast

• Interventions for treating wrist fractures in children 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 65 participants
  Low

Summary of findings. Removable splintage vs cast

It is very uncertain whether summary of findings. Removable splintage changes treatment failure (4 weeks compared with cast (very low certainty).

• Interventions for treating wrist fractures in children 2018 · Cochrane Headline outcomes only
  RR 0.71 [0.26, 1.89]
  4 studies · 444 participants
  Very low

Summary of findings. Removable splintage vs cast

• Interventions for treating wrist fractures in children 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 87 participants
  GRADE not reported

Summary of findings. Removable splintage vs cast

The review found no eligible studies for this question.

• Interventions for treating wrist fractures in children 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings. Removable splintage vs cast

• Interventions for treating wrist fractures in children 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 50 participants
  Very low

Summary of findings. Removable splintage vs cast

• Interventions for treating wrist fractures in children 2018 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 500 participants
  GRADE not reported

Summary of findings. Removable splintage vs cast

• Interventions for treating wrist fractures in children 2018 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 178 participants
  GRADE not reported

Summary of findings: Proteolytic enzymes vs placebo or control

The review found no eligible studies for this question.

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: Proteolytic enzymes vs placebo or control

Summary of findings: Proteolytic enzymes may leads to lower acute and late GI toxicity (grade 2+) compared with control (placebo or no intervention) (low certainty).

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  RR 0.45 [0.24, 0.88]
  1 study · 120 participants
  Low

Summary of findings: Proteolytic enzymes vs placebo or control

It is very uncertain whether summary of findings: Proteolytic enzymes changes diarrhoea (grade 2+) compared with control (placebo or no intervention) (very low certainty).

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  RR 1.6 [0.89, 2.89]
  1 study · 56 participants
  Very low

Summary of findings: Proteolytic enzymes vs placebo or control

The review found no eligible studies for this question.

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: Reduced dose volume vs standard dose volume

The review found no eligible studies for this question.

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: Reduced dose volume vs standard dose volume

Summary of findings: Reduced dose volume showed no clear difference in acute and late GI toxicity (grade 2+) compared with standard dose volume (moderate certainty).

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  RR 1.21 [0.81, 1.81]
  1 study · 211 participants
  Moderate

Summary of findings: Reduced dose volume vs standard dose volume

The review found no eligible studies for this question.

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: Reduced dose volume vs standard dose volume

The review found no eligible studies for this question.

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: Protein supplements vs no intervention

The review found no eligible studies for this question.

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: Protein supplements vs no intervention

The review found no eligible studies for this question.

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: Protein supplements vs no intervention

It is very uncertain whether summary of findings: Protein supplements changes diarrhoea (grade 2+) compared with no intervention (very low certainty).

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  RR 0.53 [0.27, 1.03]
  1 study · 74 participants
  Very low

Summary of findings: Protein supplements vs no intervention

The review found no eligible studies for this question.

• Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Fresh frozen plasma vs no treatment

It is very uncertain whether summary of findings: Fresh frozen plasma changes incidence of hepatic veno‐occlusive disease ( compared with no treatment (very low certainty).

• Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem cell… 2015 · Cochrane Headline outcomes only
  RR 0.66 [0.2, 2.17]
  2 studies · 383 participants
  Very low