What do systematic reviews say?

Vaccination vs placebo

Vaccination leads to lower persistence of PHN among all subjects a numerical rating scale for… compared with placebo (high certainty).

• Vaccination for preventing postherpetic neuralgia 2011 · Cochrane Headline outcomes only
  RR 0.31 [0.18, 0.54]
  1 study · 38501 participants
  High

Vaccination vs placebo

Vaccination showed no clear difference in persistence of PHN among subjects developing herpes zoster a… compared with placebo (moderate certainty).

• Vaccination for preventing postherpetic neuralgia 2011 · Cochrane Headline outcomes only
  RR 0.64 [0.38, 1.09]
  1 study · 957 participants
  Moderate

Corticosteroids vs placebo

• Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis) 2011 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 30 participants
  Low
• Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis) 2011 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 89 participants
  Low

Corticosteroids vs placebo

Corticosteroids may leads to higher complete caloric recovery compared with placebo (low certainty).

• Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis) 2011 · Cochrane Headline outcomes only
  RR 2.81 [1.32, 6]
  2 studies · 50 participants
  Low
• Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis) 2011 · Cochrane Headline outcomes only
  RR 1.58 [0.45, 5.62]
  2 studies · 89 participants
  Low

Topical methyl salicylate (Theraflex-TMJ) vs placebo

Topical methyl salicylate (Theraflex-TMJ) led to lower spontaneous masseter muscle pain (numerical graph rating scale) compared with placebo; GRADE not reported.

• Pharmacological interventions for pain in patients with temporomandibular disorders 2010 · Cochrane All outcomes

  15 days
  MD -2.00 [-2.38, -1.62]
  1 study · 52 participants
  GRADE not reported

Topical methyl salicylate (Theraflex-TMJ) vs placebo

Topical methyl salicylate (Theraflex-TMJ) led to lower spontaneous TMJ pain (numerical graph rating scale) compared with placebo; GRADE not reported.

• Pharmacological interventions for pain in patients with temporomandibular disorders 2010 · Cochrane All outcomes

  15 days
  MD -0.90 [-1.35, -0.45]
  1 study · 52 participants
  GRADE not reported

Intervention not reported

• Behavioural treatment for chronic low‐back pain 2010 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 61 participants
  Low

Intervention not reported

• Behavioural treatment for chronic low‐back pain 2010 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 47 participants
  Very low

Intervention not reported

• Behavioural treatment for chronic low‐back pain 2010 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 51 participants
  Very low

Intervention not reported

• Behavioural treatment for chronic low‐back pain 2010 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 77 participants
  Low

Intervention not reported

• Behavioural treatment for chronic low‐back pain 2010 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 61 participants
  Low

Intervention not reported

• Behavioural treatment for chronic low‐back pain 2010 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 66 participants
  Low

Summary of findings: Behavioural treatments vs waiting list control

• Behavioural treatment for chronic low‐back pain 2010 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 74 participants
  Low

Summary of findings: Behavioural treatments + other treatments vs other treatments alone

• Behavioural treatment for chronic low‐back pain 2010 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 59 participants
  Low
• Behavioural treatment for chronic low‐back pain 2010 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 51 participants
  Low

Summary of findings: Behavioural treatments vs waiting list control

• Behavioural treatment for chronic low‐back pain 2010 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 87 participants
  Low

Intervention not reported

The review found no eligible studies for this question.

• Speed cameras for the prevention of road traffic injuries and deaths 2010 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

ZOTEPINE vs CLOZAPINE

• Zotepine versus other atypical antipsychotics for schizophrenia 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 59 participants
  Very low

Total Shoulder Arthroplasty vs hemiarthroplasty

• Surgery for shoulder osteoarthritis 2010 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 88 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in drupout ‐ Tricyclics versus placebo (moderate certainty).

• Pharmacological treatment for depression during opioid agonist treatment for opioid dependence 2010 · Cochrane Headline outcomes only
  RR 1.01 [0.74, 1.37]
  3 studies · 218 participants
  Moderate

Intervention not reported

The intervention probably leads to higher severity of depression dichotomous measures ‐ Tricyclics versus… (moderate certainty).

• Pharmacological treatment for depression during opioid agonist treatment for opioid dependence 2010 · Cochrane Headline outcomes only
  RR 1.92 [1.26, 2.94]
  2 studies · 183 participants
  Moderate