Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,773 questions · 1,817 findings · 212 reviews · Headline outcomes only

No studies found 383 · 21.1%GRADE not reported 192 · 10.6%Very low 472 · 26%Low 444 · 24.4%Moderate 228 · 12.5%High 98 · 5.4%

Intervention not reported

Finding 19: social exclusion. Some parents, predominantly from LMICs, were less accepting of childhood vaccination due to their experiences of social exclusion. Social exclusion may involve economic disadvantage, residential segregation, a lack of... · groups. Numerous parents characterised infants and young children as weak and vulnerable, and in need of protection against multiple…
1 finding from 1 review

Discontinuation by "tapering" vs usual family planning care

Relapse · participants with depressive or anxiety disorders

It is very uncertain whether discontinuation by "tapering" changes relapse (as defined by study authors) (HR) compared with continuation (or usual care) (very low certainty).

1 finding from 1 review

Discontinuation by "tapering" vs usual family planning care

Adverse events · participants with depressive or anxiety disorders

It is very uncertain whether discontinuation by "tapering" changes adverse events compared with continuation (or usual care) (very low certainty).

1 finding from 1 review

Discontinuation with high‐intensity psychological interventions vs continuation

Risk of relapse (as defined by study authors) (HR) · participants with long‐term antidepressants for depressive disorders

Discontinuation with high‐intensity psychological interventions showed no clear difference in risk of relapse (as defined by study authors) (HR) compared with continuation (low certainty).

1 finding from 1 review

Abrupt discontinuation vs continuation of long‐term antidepressants

Relapse · participants with depressive or anxiety disorders

It is very uncertain whether abrupt discontinuation changes relapse (as defined by study authors) (HR) compared with continuation of long‐term antidepressants (very low certainty).

1 finding from 1 review