Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,543 questions · 2,589 findings · 168 reviews · Schizophrenia

No studies found 601 · 23.2%GRADE not reported 446 · 17.2%Very low 721 · 27.8%Low 505 · 19.5%Moderate 274 · 10.6%High 42 · 1.6%

FLUPHENAZINE (ORAL) vs OLANZAPINE

Clinically important response (defined by study) ‐ short term (up to 12 weeks) decreased rate of PANSS score < 40%, decreased rate of BPRS score < 40% · patients with schizophrenia

It is very uncertain whether FLUPHENAZINE (ORAL) changes clinically important response (defined by study) ‐ short term (up to… compared with OLANZAPINE (very low certainty).

1 finding from 1 review

FLUPHENAZINE (ORAL) vs AMISULPRIDE

Adverse effects: Extrapyramidal effects ‐ concomitant anticholinergic medication ‐ short term (up to 12 weeks) Participants requiring concomitant anticholinergic medication · patients with schizophrenia

It is very uncertain whether FLUPHENAZINE (ORAL) changes adverse effects: Extrapyramidal effects ‐ concomitant… compared with AMISULPRIDE (very low certainty).

1 finding from 1 review

FLUPHENAZINE (ORAL) vs RISPERIDONE

Clinically important response (defined by study) ‐ short term (up to 12 weeks) decreased rate of BPRS score < 20% · patients with schizophrenia

It is very uncertain whether FLUPHENAZINE (ORAL) changes clinically important response (defined by study) ‐ short term (up to… compared with RISPERIDONE (very low certainty).

1 finding from 1 review

Intervention not reported

Clinical improvement in pulse rate · adults with schizophrenia or related disorders treated for clozapine‐induced tachycardia

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Improvement in heart rate · adults with schizophrenia or related disorders treated for clozapine‐induced tachycardia

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Duration of hospitalisation · adults with schizophrenia or related disorders treated for clozapine‐induced tachycardia

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Clinically important adverse events · adults with schizophrenia or related disorders treated for clozapine‐induced tachycardia

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Patient satisfaction · adults with schizophrenia or related disorders treated for clozapine‐induced tachycardia

The review found no eligible studies for this question.

1 finding from 1 review