Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,667 questions · 21,760 findings · 2,177 reviews

No studies found 4,173 · 19.2%GRADE not reported 2,300 · 10.6%Very low 5,276 · 24.2%Low 5,764 · 26.5%Moderate 3,298 · 15.2%High 949 · 4.4%

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Progesterone vs no treatment or placebo (route of progesterone administration)

Live birth or ongoing pregnancy · women trying to conceive by intrauterine insemination

Progesterone showed no clear difference in live birth/ongoing pregnancy rate compared with no treatment or placebo (route of progesterone administration) (low certainty).

1 finding from 1 review

Intramuscular (IM) progesterone vs vaginal progesterone

Clinical pregnancy rate · women trying to conceive by intrauterine insemination

It is very uncertain whether intramuscular (IM) progesterone changes clinical pregnancy rate compared with vaginal progesterone (very low certainty).

1 finding from 1 review

Progesterone vs no treatment or placebo (route of progesterone administration)

Miscarriage per clinical pregnancy · women trying to conceive by intrauterine insemination

Progesterone showed no clear difference in miscarriage per clinical pregnancy compared with no treatment or placebo (route of progesterone administration) (low certainty).

1 finding from 1 review