Intervention not reported
Ofatumumab No direct evidence · Patients with RRMS Interventions: Alemtuzumab, cladribine, daclizumab, dimethylfumarate, fingolimod, glatiramer acetate, interferon…
It is very uncertain whether the intervention changes ofatumumab No direct evidence (very low certainty).
1 finding from 1 review
OR 1.52 [0.89, 2.57]
Studies not reported
Very low
Intervention not reported
Ozanimod No direct evidence · Patients with RRMS Interventions: Alemtuzumab, cladribine, daclizumab, dimethylfumarate, fingolimod, glatiramer acetate, interferon…
It is very uncertain whether the intervention changes ozanimod No direct evidence (very low certainty).
1 finding from 1 review
OR 1.5 [0.85, 2.64]
Studies not reported
Very low
Intervention not reported
Teriflunomide (Direct evidence; 2 RCTs; 2253 participants) · Patients with RRMS Interventions: Alemtuzumab, cladribine, daclizumab, dimethylfumarate, fingolimod, glatiramer acetate, interferon…
It is very uncertain whether the intervention changes teriflunomide (Direct evidence; 2 RCTs; 2253 participants) (very low certainty).
1 finding from 1 review
Intervention not reported
Placebo · Patients with RRMS Interventions: Alemtuzumab, cladribine, daclizumab, dimethylfumarate, fingolimod, glatiramer acetate, interferon…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Total studies: 38 Total participants: 12,985 · people with chronic pain Interventions: duloxetine (all doses combined), milnacipran (all doses combined), mirtazapine (all doses…
1 finding from 1 review
no estimate extracted
38 participants
GRADE not reported
Intervention not reported
Mirtazapine RCTs: 1 Participants: 406 · people with chronic pain Interventions: duloxetine (all doses combined), milnacipran (all doses combined), mirtazapine (all doses…
1 finding from 1 review
no estimate extracted
1 participants
Low
Intervention not reported
Duloxetine RCTs: 26 Participants: 7952 · people with chronic pain Interventions: duloxetine (all doses combined), milnacipran (all doses combined), mirtazapine (all doses…
1 finding from 1 review
no estimate extracted
26 participants
Moderate
Intervention not reported
Milnacipran RCTs: 5 Participants: 3109 · people with chronic pain Interventions: duloxetine (all doses combined), milnacipran (all doses combined), mirtazapine (all doses…
1 finding from 1 review
no estimate extracted
5 participants
Moderate
Intervention not reported
RT vs supportive care only · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option
1 finding from 1 review
Intervention not reported
Hypofractionated RT vs standard RT (60Gy/30 fractions) · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option
1 finding from 1 review
Intervention not reported
TMZ vs RT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option
1 finding from 1 review
Intervention not reported
CRT vs RT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option
1 finding from 1 review
Intervention not reported
BEV_CRT vs CRT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option
1 finding from 1 review
Intervention not reported
BEV_RT vs RT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option
1 finding from 1 review
Intervention not reported
RIN_CRT vs control/CRT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option
1 finding from 1 review
Intervention not reported
TTF_AC vs CRT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option
1 finding from 1 review
Intervention not reported
IRI_BEV_RT vs CRT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option
1 finding from 1 review
Intervention not reported
RT vs supportive care only · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option
The intervention probably leads to lower RT vs supportive care only (moderate certainty).
1 finding from 1 review
Intervention not reported
Hypofractionated RT vs standard RT (60Gy/30 fractions) · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option
The intervention led to lower hypofractionated RT vs standard RT (60Gy/30 fractions); GRADE not reported.
1 finding from 1 review
Intervention not reported
TMZ vs RT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option
The intervention showed no clear difference in TMZ vs RT (low certainty).
1 finding from 1 review