Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,966 questions · 3,201 findings · 165 reviews

No studies found 25 · 0.8%GRADE not reported 2,717 · 84.9%Very low 167 · 5.2%Low 124 · 3.9%Moderate 132 · 4.1%High 36 · 1.1%

Intervention not reported

Dental caries in permanent teeth · Children (permanent dentition) worldwide

In Europe, the pooled prevalence of permanent-teeth caries in children was 44.1% (95% CI 36.1 to 52.5); certainty not graded.

1 finding from 1 review

LTF rs11716497 variant vs Reference allele/genotype

Dental caries · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

LTF rs11716497 showed no significant association with dental caries in a single study (OR 1.04, 95% CI 0.90 to 1.21; ungraded).

1 finding from 1 review

Intervention not reported

Dental caries in permanent teeth · Children (permanent dentition) worldwide

In Australia, the pooled estimate of permanent-teeth caries prevalence in children was 54.9% (95% CI 50.9 to 58.8) from a single study; certainty not graded.

1 finding from 1 review

LTF rs1126477 variant vs Reference allele/genotype

Dental caries · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

LTF rs11216477 was significantly associated with dental caries in a single study (OR 1.17, 95% CI 1.06 to 1.29; ungraded).

1 finding from 1 review