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Evidence found and GRADE certainty

4,815 questions · 6,211 findings · 638 reviews · Headline outcomes only

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No studies found 1,052 · 16.9%GRADE not reported 441 · 7.1%Very low 1,700 · 27.4%Low 1,651 · 26.6%Moderate 1,070 · 17.2%High 297 · 4.8%

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GnRHa treatment vs placebo

Relief of overall pain ‐ reported as pelvic tenderness ‐ 6 months · women with endometriosis

GnRHas may leads to higher relief of overall pain ‐ reported as pelvic tenderness scores‐ 3… compared with placebo (low certainty).

1 finding from 1 review

GnRHa treatment vs placebo

Relief of overall pain ‐ reported as pelvic induration ‐ 6 months · women with endometriosis

GnRHas showed no clear difference in relief of overall pain ‐ reported as pelvic induration scores ‐ 3… compared with placebo (low certainty).

1 finding from 1 review

GnRHa treatment vs danazol

Relief of overall pain ‐ reported as pelvic tenderness, partly resolved ‐ 6 months · patients with pain associated with endometriosis

It is very uncertain whether gnRHas changes relief of overall pain ‐ reported as pelvic tenderness, partly… compared with danazol (very low certainty).

1 finding from 1 review

GnRHa treatment vs danazol

Relief of overall pain ‐ reported as pelvic tenderness, complete resolved ‐ 6 months · patients with pain associated with endometriosis

It is very uncertain whether gnRHas changes relief of overall pain ‐ reported as pelvic tenderness, complete… compared with danazol (very low certainty).

1 finding from 1 review

Caffeine vs other methylxanthines

c) Developmental delay more than two SDs below population mean on a standardized test of development: cognitive delay № of participants: 79(1 RCT) · preterm infants

It is very uncertain whether caffeine changes c) Developmental delay more than two SDs below population mean on a… compared with other methylxanthines (very low certainty).

1 finding from 1 review

Caffeine vs other methylxanthines

c) Developmental delay more than two SDs below population mean on a standardized test of development: language delay № of participants: 79(1 RCT) · preterm infants

It is very uncertain whether caffeine changes c) Developmental delay more than two SDs below population mean on a… compared with other methylxanthines (very low certainty).

1 finding from 1 review

Caffeine vs other methylxanthines

c) Developmental delay more than two SDs below population mean on a standardized test of development: motor delay № of participants: 79(1 RCT) · preterm infants

It is very uncertain whether caffeine changes c) Developmental delay more than two SDs below population mean on a… compared with other methylxanthines (very low certainty).

1 finding from 1 review