Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,411 questions · 5,986 findings · 226 reviews · Oral Health

No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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Powered toothbrushing (as part of comprehensive oral care) vs Manual toothbrushing

Duration of ICU stay · Critically ill patients receiving mechanical ventilation in ICU

Powered toothbrushing (as part of comprehensive oral care) showed no clear difference in duration of ICU stay compared with manual toothbrushing (standard oral care); GRADE not reported.

1 finding from 1 review

Counter-stimulation or distraction vs Conventional treatment

Patient satisfaction: measured by questionnaires · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Clobetasol propionate ointment vs Clobetasol propionate 0.025% ointment

Clinical score · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Clobetasol propionate 0.05% ointment showed no clear difference in clinical score compared with clobetasol propionate 0.025% ointment (low certainty).

1 finding from 1 review

Topical triamcinolone acetonide vs Topical ciclosporin

Pain (mean VAS score) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Topical triamcinolone acetonide showed no clear difference in pain (mean VAS score) compared with topical ciclosporin; GRADE not reported.

1 finding from 1 review

Counter-stimulation or distraction vs Conventional treatment

Adverse effects · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Camouflage syringe vs Conventional syringe

Completion of dental treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Any method, procedure or policy to reduce contaminated aerosols in dental clinics vs Any other method, no treatment or combination of methods

Reduction in volume of contaminated aerosols in the operative environment · Dental healthcare providers (dentist, dental surgery assistant, dental hygienist, dental technologist, dental laboratory staff, dental…

The review found no eligible studies for this question.

1 finding from 1 review

Electrical counter-stimulation device (DentalVibe) vs Conventional treatment (no stimulation)

Patient satisfaction: measured by questionnaires · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Radiographic examination (bitewing radiographs) vs Reference standard: histology

Sensitivity · Extracted molar teeth of adults with resin composite approximal restorations (in vitro; secondary root caries; Switzerland)
1 finding from 1 review
  • 2 in vitro studies (59 root surfaces) using extracted, restored teeth and a histological reference standard investigated the accuracy of radiographs. Reported estimates of sensitivity ranged from 0.40 to 0.63 and…
    2 studies
    Very low

Combined index test: visual examination + radiograph + DIAGNOdent (Alomari 2015) vs Reference standard: histology

Specificity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review

Clobetasol propionate ointment vs Clobetasol propionate 0.025% ointment

Clinical resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether clobetasol propionate 0.05% ointment changes clinical resolution compared with clobetasol propionate 0.025% ointment (very low certainty).

1 finding from 1 review

Counter-stimulation or distraction vs Conventional treatment

Adverse effects: pain on injection (solution deposition), Heft-Parker VAS 0-170 mm · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

Counter-stimulation or distraction led to lower pain on injection (Wong-Baker Faces / TPPPS / FPS-R, after LA) compared with conventional treatment; GRADE not reported.

1 finding from 1 review

Pre-cooling of the injection site vs Conventional treatment

Adverse effects · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Video modelling acclimatisation vs Acclimatisation in clinic (tell-show-do)

Self- or observational assessment of intraoperative distress/pain/acceptance of treatment during provision of LA: pain-related behaviour during LA (negative vs positive behaviour; Frankl Behaviour Rating Scale) · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

It is very uncertain whether video modelling acclimatisation changes self- or observational assessment of intraoperative… compared with acclimatisation in clinic (tell-show-do) (very low certainty).

1 finding from 1 review

Surgical removal (extraction) of asymptomatic disease-free impacted wisdom teeth vs Retention (conservative management) of asymptomatic disease-free impacted wisdom teeth

Arch length (dental arch dimensional change) · Adolescents or adults with asymptomatic disease-free impacted wisdom teeth

Surgical removal (extraction) of asymptomatic disease-free impacted… may leads to lower arch length (dimensional changes in the dental arch) compared with retention (conservative management) of asymptomatic disease-free… (low certainty).

1 finding from 1 review

Antimicrobial mouthwash and/or nasal spray (alone or in combination), any concentration, frequency or dosage vs No treatment or saline or water

Change in viral load · Patients with suspected or confirmed COVID-19 infection

The review found no eligible studies for this question.

1 finding from 1 review

Clinical examination with risk-based recall vs Clinical examination with 6-month recall

Dental caries: prevalence of moderate to extensive caries (ICDAS 3-6) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with risk-based recall showed no clear difference in dental caries: prevalence of moderate to extensive caries (ICDAS 3-6) compared with clinical examination with 6-month recall (moderate certainty).

1 finding from 1 review