Intervention not reported
Cladribine (Direct evidence; 1 RCT; 1326 participants) · Patients with RRMS Interventions: Alemtuzumab, cladribine, daclizumab, dimethylfumarate, fingolimod, glatiramer acetate, interferon…
It is very uncertain whether the intervention changes cladribine (Direct evidence; 1 RCT; 1326 participants) (very low certainty).
1 finding from 1 review
Intervention not reported
Daclizumab (Direct evidence; 1 RCT; 600 participants) · Patients with RRMS Interventions: Alemtuzumab, cladribine, daclizumab, dimethylfumarate, fingolimod, glatiramer acetate, interferon…
The intervention may leads to higher daclizumab (Direct evidence; 1 RCT; 600 participants) (low certainty).
1 finding from 1 review
Intervention not reported
Fingolimod (Direct evidence; 2 RCTs; 2355 participants) · Patients with RRMS Interventions: Alemtuzumab, cladribine, daclizumab, dimethylfumarate, fingolimod, glatiramer acetate, interferon…
The intervention showed no clear difference in fingolimod (Direct evidence; 2 RCTs; 2355 participants) (low certainty).
1 finding from 1 review
Intervention not reported
Glatiramer acetate (Direct evidence; 3 RCTs; 2371 participants) · Patients with RRMS Interventions: Alemtuzumab, cladribine, daclizumab, dimethylfumarate, fingolimod, glatiramer acetate, interferon…
The intervention showed no clear difference in glatiramer acetate (Direct evidence; 3 RCTs; 2371 participants) (low certainty).
1 finding from 1 review
Intervention not reported
Interferon beta‐1b (Betaferon) No direct evidence · Patients with RRMS Interventions: Alemtuzumab, cladribine, daclizumab, dimethylfumarate, fingolimod, glatiramer acetate, interferon…
The intervention showed no clear difference in interferon beta‐1b (Betaferon) No direct evidence (moderate certainty).
1 finding from 1 review
OR 0.92 [0.55, 1.54]
1 participants
Moderate
Intervention not reported
Interferon beta‐1a (Rebif, Avonex) (Direct evidence; 1 RCT; 897 participants) · Patients with RRMS Interventions: Alemtuzumab, cladribine, daclizumab, dimethylfumarate, fingolimod, glatiramer acetate, interferon…
It is very uncertain whether the intervention changes interferon beta‐1a (Rebif, Avonex) (Direct evidence; 1 RCT; 897… (very low certainty).
1 finding from 1 review
Intervention not reported
Laquinimod (Direct evidence; 3 RCTs; 3457 participants) · Patients with RRMS Interventions: Alemtuzumab, cladribine, daclizumab, dimethylfumarate, fingolimod, glatiramer acetate, interferon…
It is very uncertain whether the intervention changes laquinimod (Direct evidence; 3 RCTs; 3457 participants) (very low certainty).
1 finding from 1 review
Intervention not reported
Pegylated interferon beta‐1a (Direct evidence; 1 RCT; 1512 participants) · Patients with RRMS Interventions: Alemtuzumab, cladribine, daclizumab, dimethylfumarate, fingolimod, glatiramer acetate, interferon…
It is very uncertain whether the intervention changes pegylated interferon beta‐1a (Direct evidence; 1 RCT; 1512… (very low certainty).
1 finding from 1 review
Intervention not reported
Mitoxantrone (Direct evidence; 1 RCT; 53 participants) · Patients with RRMS Interventions: Alemtuzumab, cladribine, daclizumab, dimethylfumarate, fingolimod, glatiramer acetate, interferon…
It is very uncertain whether the intervention changes mitoxantrone (Direct evidence; 1 RCT; 53 participants) (very low certainty).
1 finding from 1 review
Intervention not reported
Natalizumab (Direct evidence; 1 RCT; 939 participants) · Patients with RRMS Interventions: Alemtuzumab, cladribine, daclizumab, dimethylfumarate, fingolimod, glatiramer acetate, interferon…
The intervention showed no clear difference in natalizumab (Direct evidence; 1 RCT; 939 participants) (low certainty).
1 finding from 1 review
Intervention not reported
Ocrelizumab No direct evidence · Patients with RRMS Interventions: Alemtuzumab, cladribine, daclizumab, dimethylfumarate, fingolimod, glatiramer acetate, interferon…
It is very uncertain whether the intervention changes ocrelizumab No direct evidence (very low certainty).
1 finding from 1 review
OR 1 [0.58, 1.72]
Studies not reported
Very low
Intervention not reported
Ofatumumab No direct evidence · Patients with RRMS Interventions: Alemtuzumab, cladribine, daclizumab, dimethylfumarate, fingolimod, glatiramer acetate, interferon…
It is very uncertain whether the intervention changes ofatumumab No direct evidence (very low certainty).
1 finding from 1 review
OR 1.52 [0.89, 2.57]
Studies not reported
Very low
Intervention not reported
Ozanimod No direct evidence · Patients with RRMS Interventions: Alemtuzumab, cladribine, daclizumab, dimethylfumarate, fingolimod, glatiramer acetate, interferon…
It is very uncertain whether the intervention changes ozanimod No direct evidence (very low certainty).
1 finding from 1 review
OR 1.5 [0.85, 2.64]
Studies not reported
Very low
Intervention not reported
Ponesimod No direct evidence · Patients with RRMS Interventions: Alemtuzumab, cladribine, daclizumab, dimethylfumarate, fingolimod, glatiramer acetate, interferon…
It is very uncertain whether the intervention changes ponesimod No direct evidence (very low certainty).
1 finding from 1 review
OR 1.24 [0.66, 2.35]
Studies not reported
Very low
Intervention not reported
Teriflunomide (Direct evidence; 2 RCTs; 2253 participants) · Patients with RRMS Interventions: Alemtuzumab, cladribine, daclizumab, dimethylfumarate, fingolimod, glatiramer acetate, interferon…
It is very uncertain whether the intervention changes teriflunomide (Direct evidence; 2 RCTs; 2253 participants) (very low certainty).
1 finding from 1 review
Intervention not reported
Placebo · Patients with RRMS Interventions: Alemtuzumab, cladribine, daclizumab, dimethylfumarate, fingolimod, glatiramer acetate, interferon…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Depression Hospital Anxiety and Depression Scale (HADS) or Beck Inventory Score (HADS score range from 0 to 21 and Beck Inventory Score range from 0 to 63) · Women with non‐metastatic breast cancer
1 finding from 1 review
Anxiety · Women with non‐metastatic breast cancer
1 finding from 1 review
Mood disturbance Profile of mood state (higher score indicates more mood disturbance, score range from 0 to 200) · Women with non‐metastatic breast cancer
1 finding from 1 review
QoL · Women with non‐metastatic breast cancer
1 finding from 1 review