Overall survival: higher‐dose WBRT vs control (3000 cGy/10 daily fractions)No. of participants: 846(4 RCTs) · patients with newly diagnosed multiple brain metastases
Altered WBRT fractionation schedules probably leads to higher overall survival: lower‐dose WBRT vs control WBRT (3000 cGy/10 daily… compared with WBRT control (moderate certainty).
1 finding from 1 review
HR 1.21 [1.04, 1.4]
Studies not reported
Moderate
Neurological function improvement: lower‐dose WBRT vs control dose WBRT (3000 cGy/10 fractions)No. of participants: 1612(5 RCTs) · patients with newly diagnosed multiple brain metastases
Altered WBRT fractionation schedules probably leads to higher neurological function improvement: lower‐dose WBRT vs control dose… compared with WBRT control: neurological function improvement (moderate certainty).
1 finding from 1 review
OR 1.74 [1.06, 2.84]
Studies not reported
Moderate
Intervention not reported
Pain: 50% reduction in headache frequency Post‐treatment Lower scores = fewer headaches · Children and adolescents with chronic pain
It is very uncertain whether the intervention changes pain: 50% reduction in headache frequency Post‐treatment Lower… (very low certainty).
1 finding from 1 review
Intervention not reported
Disability Post‐treatment Lower scores = lower reported disability · Children and adolescents with chronic pain
1 finding from 1 review
Intervention not reported
Anxiety Post‐treatment Lower scores = lower reported anxiety · Children and adolescents with chronic pain
1 finding from 1 review
Intervention not reported
Depression Post‐treatment Lower scores = lower reported depression · Children and adolescents with chronic pain
1 finding from 1 review
Intervention not reported
Disability Post‐treatment Lower scores = lower reported disability · Children and adolescents with chronic pain
1 finding from 1 review
Intervention not reported
Anxiety Post‐treatment Lower scores = lower reported anxiety · Children and adolescents with chronic pain
1 finding from 1 review
Intervention not reported
Depression Post‐treatment Lower scores = lower reported depression · Children and adolescents with chronic pain
1 finding from 1 review
Intervention not reported
Pain Post‐treatment Lower scores = lower reported pain intensity · Children and adolescents with chronic pain
1 finding from 1 review
Depression (lower scores mean less depression) · clinical diagnosis of depression
1 finding from 1 review
Depression (lower scores mean less depression) · clinical diagnosis of depression
1 finding from 1 review
Intervention not reported
Caesarean section ‐ low risk group · nurses, midwives, physicians
The intervention showed no clear difference in caesarean section ‐ low risk group (high certainty).
1 finding from 1 review
no estimate extracted
Studies not reported
High
Intervention not reported
Activities of daily living (ADL) (Barthel Index score 0 to 20; lower = 0; median 3‐month · adults with acute stroke
The intervention showed no clear difference in activities of daily living (ADL) (Barthel Index score 0 to 20; lower… (low certainty).
1 finding from 1 review
Intervention not reported
Subjective Health Status score (Assessment of Quality of Life Score 0 to 1; lower = 0; end of scheduled · adults with acute stroke
It is very uncertain whether the intervention changes subjective Health Status score (Assessment of Quality of Life Score… (very low certainty).
1 finding from 1 review
Low cord pH · women in the second stage of labour with epidural anaesthesia
Upright position probably leads to lower low cord pH compared with recumbent position (moderate certainty).
1 finding from 1 review
Incidence of upper body disorders (neck, shoulder, and upper extremity) Questionnaire followed by medical examination · office workers
Arm support combined with alternative mouse showed no clear difference in incidence of upper body disorders (neck, shoulder, and upper… compared with conventional mouse alone (moderate certainty).
1 finding from 1 review
Incidence of upper body disorders (neck, shoulder, and upper extremity) Questionnaire followed by medical examination · office workers
Alternative mouse alone showed no clear difference in incidence of upper body disorder (neck, shoulder and upper… compared with conventional mouse alone (moderate certainty).
1 finding from 1 review
Incidence of neck/shoulder disorder Questionnaire followed by medical examination · office workers
Alternative mouse alone showed no clear difference in incidence of neck or shoulderdisorder Questionnaire followed by… compared with conventional mouse alone (low certainty).
1 finding from 1 review
Incidence of right upper extremity disorder Questionnaire followed by medical examination · office workers
Alternative mouse alone showed no clear difference in incidence of right upper extremity disorder Questionnaire followed… compared with conventional mouse alone (moderate certainty).
1 finding from 1 review