Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,532 questions · 2,642 findings · 483 reviews · Headline outcomes only

No studies found 534 · 20.2%GRADE not reported 82 · 3.1%Very low 641 · 24.3%Low 807 · 30.5%Moderate 472 · 17.9%High 106 · 4%

Aspirin vs placebo

Total mortality · adults with hypertension (patients with atrial fibrillation, congestive heart failure, pre‐eclampsia or pulmonary hypertension were…

Aspirin showed no clear difference in total mortality compared with placebo (low certainty).

1 finding from 1 review

Aspirin vs placebo

Cardiovascular mortality · adults with hypertension (patients with atrial fibrillation, congestive heart failure, pre‐eclampsia or pulmonary hypertension were…

Aspirin showed no clear difference in cardiovascular mortality compared with placebo (low certainty).

1 finding from 1 review

Aspirin vs placebo

Non‐fatal cardiovascular events · adults with hypertension (patients with atrial fibrillation, congestive heart failure, pre‐eclampsia or pulmonary hypertension were…

Aspirin may leads to lower non‐fatal cardiovascular events compared with placebo (low certainty).

1 finding from 1 review

Aspirin vs placebo

Major bleedinga · adults with hypertension (patients with atrial fibrillation, congestive heart failure, pre‐eclampsia or pulmonary hypertension were…

Aspirin leads to higher major bleedinga compared with placebo (high certainty).

1 finding from 1 review

Aspirin vs placebo

Cardiovascular events · adults with hypertension (patients with atrial fibrillation, congestive heart failure, pre‐eclampsia or pulmonary hypertension were…

Aspirin may leads to lower all cardiovascular events compared with placebo (low certainty).

1 finding from 1 review