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Evidence found and GRADE certainty

122 questions · 126 findings · 21 reviews · Headline outcomes only

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No studies found 23 · 18.3%GRADE not reported 1 · 0.8%Very low 26 · 20.6%Low 44 · 34.9%Moderate 30 · 23.8%High 2 · 1.6%

Extended peginterferon plus ribavirin treatment for 72 weeks vs standard peginterferon plus ribavirin treatment

End of treatment response (ETR) · participants with detectable HCV RNA after four weeks of treatment with pegylated interferon and ribavirin

Extended peginterferon plus ribavirin treatment for 72 weeks may leads to lower end of treatment response (ETR) compared with standard peginterferon plus ribavirin treatment (low certainty).

1 finding from 1 review

Extended peginterferon plus ribavirin treatment for 72 weeks vs standard peginterferon plus ribavirin treatment

Adherance to treatment · participants with detectable HCV RNA after four weeks of treatment with pegylated interferon and ribavirin or participants with detectable…

Extended peginterferon plus ribavirin treatment for 72 weeks probably leads to lower adherance to treatment compared with standard peginterferon plus ribavirin treatment (moderate certainty).

1 finding from 1 review