Findings

What do systematic reviews say?

130 questions · 134 findings · 10 reviews · Haematology

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No studies found 43 · 32.1%GRADE not reported 16 · 11.9%Very low 32 · 23.9%Low 30 · 22.4%Moderate 11 · 8.2%High 2 · 1.5%

Intervention not reported

Incidence of severe infections (Grade III or IV) · cancer patients receiving myelotoxic chemotherapy

The intervention showed no clear difference in incidence of severe infections (Grade III or IV) (low certainty).

1 finding from 1 review

Prophylactic antibiotics or G(M)‐CSF for the prevention of infections and improvement of survival in cancer patients… 2015 · Cochrane Headline outcomes only
RR 1.55 [0.86, 2.8]
1 study · 115 participants
Low

Intervention not reported

Adverse events Toxic deaths · cancer patients receiving myelotoxic chemotherapy

The intervention showed no clear difference in adverse events Toxic deaths (low certainty).

1 finding from 1 review

Prophylactic antibiotics or G(M)‐CSF for the prevention of infections and improvement of survival in cancer patients… 2015 · Cochrane Headline outcomes only
RR 1.32 [0.3, 5.69]
1 study · 115 participants
Low

Intervention not reported

Infection‐related mortality · cancer patients receiving myelotoxic chemotherapy

1 finding from 1 review

Prophylactic antibiotics or G(M)‐CSF for the prevention of infections and improvement of survival in cancer patients… 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Very low

Intervention not reported

Quality of life · cancer patients receiving myelotoxic chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic antibiotics or G(M)‐CSF for the prevention of infections and improvement of survival in cancer patients… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Incidence of febrile neutropenia · cancer patients receiving myelotoxic chemotherapy

It is very uncertain whether the intervention changes incidence of febrile neutropenia (very low certainty).

1 finding from 1 review

Prophylactic antibiotics or G(M)‐CSF for the prevention of infections and improvement of survival in cancer patients… 2015 · Cochrane Headline outcomes only
RR 1.22 [0.53, 2.84]
1 study · 40 participants
Very low

Intervention not reported

Incidence of severe infections · cancer patients receiving myelotoxic chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic antibiotics or G(M)‐CSF for the prevention of infections and improvement of survival in cancer patients… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Adverse events · cancer patients receiving myelotoxic chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic antibiotics or G(M)‐CSF for the prevention of infections and improvement of survival in cancer patients… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

All cause mortality · cancer patients receiving myelotoxic chemotherapy

1 finding from 1 review

Prophylactic antibiotics or G(M)‐CSF for the prevention of infections and improvement of survival in cancer patients… 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 115 participants
Low

Intervention not reported

Infection‐related mortality · cancer patients receiving myelotoxic chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic antibiotics or G(M)‐CSF for the prevention of infections and improvement of survival in cancer patients… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Quality of life · cancer patients receiving myelotoxic chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic antibiotics or G(M)‐CSF for the prevention of infections and improvement of survival in cancer patients… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found