Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

167 questions · 167 findings · 8 reviews · Cystic Fibrosis and Genetic Disorders

No studies found 80 · 47.9%GRADE not reported 1 · 0.6%Very low 45 · 26.9%Low 34 · 20.4%Moderate 7 · 4.2%High 0 · 0%

Intervention not reported

Infusion‐related reactions (number of participants with one or more reaction) · adults and children with mucopolysaccharidosis I

The intervention showed no clear difference in infusion‐related reactions (number of participants with one or more… (low certainty).

1 finding from 1 review

Intervention not reported

Antibody production: number of participants developing IgG antibodies · adults and children with mucopolysaccharidosis I

It is very uncertain whether the intervention changes antibody production: number of participants developing IgG antibodies (very low certainty).

1 finding from 1 review