Findings

What do systematic reviews say?

127 questions · 161 findings · 10 reviews

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No studies found 34 · 21.1%GRADE not reported 60 · 37.3%Very low 31 · 19.3%Low 12 · 7.5%Moderate 13 · 8.1%High 11 · 6.8%

Topical ivermectin vs topical metronidazole

Assessment of erythema or telangiectasia ‐ not measured · Participants with rosacea

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical ivermectin vs topical metronidazole

Lesion count · Participants with rosacea

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 962 participants
High

Topical ivermectin vs topical metronidazole

Time needed until improvement of the skin lesions · Participants with rosacea

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 962 participants
High

Topical ivermectin vs topical metronidazole

Duration of remission ‐ not measured · Participants with rosacea

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Doxycycline 40 mg + azelaic acid gel vs doxycycline 40 mg + metronidazole gel

HRQOL ‐ not measured · Participants with rosacea

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Doxycycline 40 mg + azelaic acid gel vs doxycycline 40 mg + metronidazole gel

Participant‐assessed improvement in rosacea severity · Participants with rosacea

Doxycycline 40 mg + azelaic acid gel showed no clear difference in participant‐assessed improvement in rosacea severity Excellent… compared with doxycycline 40 mg + metronidazole gel (high certainty).

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
RR 1.05 [0.79, 1.4]
1 study · 207 participants
High

Doxycycline 40 mg + azelaic acid gel vs doxycycline 40 mg + metronidazole gel

Proportion of participants with adverse event · Participants with rosacea

Doxycycline 40 mg + azelaic acid gel showed no clear difference in proportion of participants with adverse event compared with doxycycline 40 mg + metronidazole gel (high certainty).

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
RR 0.27 [0.06, 1.28]
1 study · 207 participants
High