Findings

What do systematic reviews say?

143 questions · 143 findings · 3 reviews · Gut

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No studies found 62 · 43.4%GRADE not reported 0 · 0%Very low 51 · 35.7%Low 23 · 16.1%Moderate 6 · 4.2%High 1 · 0.7%

Four‐food elimination and amino acid formula vs four‐food elimination diet

Clinical improvement (continuous) · active EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 41 participants
Very low

Corticosteroids vs placebo

Clinical improvement (dichotomous) · inactive EoE patients

It is very uncertain whether corticosteroids changes clinical improvement (dichotomous) compared with placebo (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 2.17 [0.75, 6.27]
2 studies · 252 participants
Very low

Four‐food elimination and amino acid formula vs four‐food elimination diet

Histological improvement (dichotomous) · active EoE patients

It is very uncertain whether four‐food elimination and amino acid formula changes histological improvement at 6 weeks (dichotomous) compared with four‐food elimination diet (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 1.9 [0.79, 4.6]
1 study · 41 participants
Very low

Four‐food elimination and amino acid formula vs four‐food elimination diet

Histological improvement (continuous) · active EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 41 participants
Very low

Four‐food elimination and amino acid formula vs four‐food elimination diet

Endoscopic improvement (dichotomous) · active EoE patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Four‐food elimination and amino acid formula vs four‐food elimination diet

Endoscopic improvement (continuous) · active EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 41 participants
Very low

Four‐food elimination and amino acid formula vs four‐food elimination diet

Withdrawals due to adverse events · active EoE patients

It is very uncertain whether four‐food elimination and amino acid formula changes withdrawals due to adverse events at 6 weeks compared with four‐food elimination diet (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 0.95 [0.06, 14.22]
1 study · 41 participants
Very low

Nebulized budesonide vs viscous budesonide

Clinical improvement (dichotomous) · active EoE patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Nebulized budesonide vs viscous budesonide

Clinical improvement (continuous) · active EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 22 participants
Very low

Nebulized budesonide vs viscous budesonide

Histological improvement (dichotomous) · active EoE patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Nebulized budesonide vs viscous budesonide

Histological improvement (continuous) · active EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 22 participants
Very low

Nebulized budesonide vs viscous budesonide

Endoscopic improvement (dichotomous) · active EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
Very low

Corticosteroids vs placebo

Clinical improvement (continuous) · inactive EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 269 participants
Very low

Nebulized budesonide vs viscous budesonide

Endoscopic improvement (continuous) · active EoE patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Nebulized budesonide vs viscous budesonide

Withdrawals due to adverse events · active EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
Very low

Viaskin milk patch vs placebo

Clinical improvement (dichotomous) · active EoE pediatric patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Viaskin milk patch vs placebo

Clinical improvement (continuous) · active EoE pediatric patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 9 participants
Low

Viaskin milk patch vs placebo

Histological improvement (dichotomous) · active EoE pediatric patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Viaskin milk patch vs placebo

Histological improvement (continuous) · active EoE pediatric patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 9 participants
Low

Viaskin milk patch vs placebo

Endoscopic improvement (dichotomous) · active EoE pediatric patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found