Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

231 questions · 245 findings · 9 reviews · Gut

No studies found 76 · 31%GRADE not reported 3 · 1.2%Very low 106 · 43.3%Low 47 · 19.2%Moderate 12 · 4.9%High 1 · 0.4%

Swallowed fluticasone vs prednisone

Withdrawals due to adverse events · active EoE pediatric patients

It is very uncertain whether swallowed fluticasone changes withdrawals due to adverse events at 4 weeks compared with oral prednisone (very low certainty).

1 finding from 1 review

Corticosteroids vs placebo

Endoscopic improvement (dichotomous) · active EoE patients

Corticosteroids showed no clear difference in endoscopic improvement (dichotomous) compared with placebo (low certainty).

1 finding from 1 review

Esomeprazole vs fluticasone

Histological improvement (dichotomous) · active EoE patients

It is very uncertain whether esomeprazole changes histological improvement at 8 weeks (dichotomous) compared with fluticasone (very low certainty).

1 finding from 1 review

Esomeprazole vs fluticasone

Withdrawals due to adverse events · active EoE patients

It is very uncertain whether esomeprazole changes withdrawals due to adverse events at 8 weeks compared with fluticasone (very low certainty).

1 finding from 1 review