Infectious complications · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
Systemic antibiotic prophylaxis (any regimen; topical therapy… may leads to lower postsurgical infectious complications compared with placebo (low certainty).
1 finding from 1 review
Swelling (7th day) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes swelling (7th day) compared with placebo (very low certainty).
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes pain (continuous, VAS 0-10 cm, 7th day) compared with placebo (very low certainty).
1 finding from 1 review
Pain (dichotomous, present/absent on 6th-7th day) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes presence of pain (dichotomous, yes/no on 6th-7th day) compared with placebo (very low certainty).
1 finding from 1 review
Adverse effects · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes adverse effects compared with placebo (very low certainty).
1 finding from 1 review
Trismus (dichotomous, 7th day) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes trismus (dichotomous, 7th day) compared with placebo (very low certainty).
1 finding from 1 review
Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs Placebo
Outcome not reported · Immunosuppressed / immunocompromised patients (e.g. HIV infection, AIDS, diabetes, transplants) undergoing tooth extraction
The review found no eligible studies for this question.
1 finding from 1 review
Fever · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes fever (6th-7th day) compared with placebo (very low certainty).
1 finding from 1 review
Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs Placebo
Outcome not reported · Patients undergoing tooth extraction for severe dental caries or periodontal disease in general dental practice (non-third-molar / decayed…
The review found no eligible studies for this question.
1 finding from 1 review
Duration of postoperative analgesia · Children up to 13 years of age, undergoing cleft lip repair surgery
The review found no eligible studies for this question.
1 finding from 1 review
Time to feeding after surgery · Children up to 13 years of age, undergoing cleft lip repair surgery
The review found no eligible studies for this question.
1 finding from 1 review
Adverse events · Children up to 13 years of age, undergoing cleft lip repair surgery
1 finding from 1 review
Length of hospital stay · Children up to 13 years of age, undergoing cleft lip repair surgery
The review found no eligible studies for this question.
1 finding from 1 review
Length of hospital stay · Children up to 13 years of age, undergoing cleft lip repair surgery
The review found no eligible studies for this question.
1 finding from 1 review
Pain measured by valid instruments (mean postoperative pain score) · Children up to 13 years of age, undergoing cleft lip repair surgery
It is very uncertain whether perioperative infraorbital nerve block changes pain measured by valid instruments (mean postoperative pain score) compared with intravenous analgesia (very low certainty).
1 finding from 1 review
Need for analgesic prescription for pain (supplemental analgesic requirements) · Children up to 13 years of age, undergoing cleft lip repair surgery
It is very uncertain whether perioperative infraorbital nerve block changes need for analgesic prescription for pain (supplemental analgesic… compared with infiltration of the incision (peri-incisional infiltration) (very low certainty).
1 finding from 1 review
Analgesia durationTime duration from the end of surgery to the time of first analgesic consumption. Scale from: 0 to 100. · Children up to 13 years of age, undergoing cleft lip repair surgery
1 finding from 1 review
Time to feeding after surgery · Children up to 13 years of age, undergoing cleft lip repair surgery
Perioperative infraorbital nerve block may leads to lower time to feeding after surgery (in minutes) compared with intravenous analgesia (low certainty).
1 finding from 1 review
Pain measured by valid instruments (mean postoperative pain score) · Children up to 13 years of age, undergoing cleft lip repair surgery
1 finding from 1 review
Need for analgesic prescription for pain (supplemental analgesic requirements) · Children up to 13 years of age, undergoing cleft lip repair surgery
It is very uncertain whether perioperative infraorbital nerve block changes need for analgesic prescription for pain (supplemental analgesic… compared with intravenous analgesia (very low certainty).
1 finding from 1 review