Findings

What do systematic reviews say?

315 questions · 322 findings · 87 reviews · Neonatal

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No studies found 47 · 14.6%GRADE not reported 18 · 5.6%Very low 78 · 24.2%Low 105 · 32.6%Moderate 50 · 15.5%High 24 · 7.5%

Clonidine and opioid vs opioid

Days' pharmacological treatment · newborn infants with opioid withdrawal

1 finding from 1 review

Sedatives for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 80 participants
Very low

Clonidine and opioid vs phenobarbital and opioid

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Sedatives for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 91 participants
Low

Clonidine and opioid vs phenobarbital and opioid

Days' pharmacological treatment · newborn infants with opioid withdrawal

1 finding from 1 review

Sedatives for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 91 participants
Low

Phenobarbital vs supportive care

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Sedatives for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 62 participants
Very low

Phenobarbital vs supportive care

Days' pharmacological treatment · newborn infants with opioid withdrawal

1 finding from 1 review

Sedatives for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 62 participants
Very low

Morphine vs methadone

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 116 participants
Low

Morphine vs methadone

Days treatment · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 147 participants
Low

Morphine vs buprenorphine

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 113 participants
Moderate

Morphine vs buprenorphine

Days treatment · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 112 participants
Moderate

Morphine vs dilute tincture of opium

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 33 participants
Low

Morphine vs dilute tincture of opium

Days treatment · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 33 participants
Low

Opioids vs clonidine

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
Low

Opioids vs clonidine

Days treatment · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
Low

Opioids vs diazepam

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Very low

Opioids vs diazepam

Days treatment · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 33 participants
Very low

Opioids vs phenobarbital

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 166 participants
Low

Opioids vs phenobarbital

Days treatment · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 349 participants
Low

Opioids vs Placebo, no intervention or usual care (with or without placebo)

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 80 participants
Very low

Opioids vs chlorpromazine

Length of hospital stay · newborn infants with opioid withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Opioids vs chlorpromazine

Days treatment · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 76 participants
Low