All‐cause mortality · cognitively healthy people in late life
Other NSAIDs showed no clear difference in mortality compared with placebo (moderate certainty).
1 finding from 1 review
Incidence of mild cognitive impairment · cognitively healthy people in late life
Other NSAIDs showed no clear difference in incidence of mild cognitive impairment compared with placebo (low certainty).
1 finding from 1 review
Activities of daily living · cognitively healthy people in late life
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Health‐related quality of life · cognitively healthy people in late life
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Incidence of dementia · older people with age‐related memory loss
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Gastrointestinal adverse events · older people with age‐related memory loss
NSAIDs (celecoxib) may leads to higher adverse events – gastrointestinal compared with placebo (low certainty).
1 finding from 1 review
All‐cause mortality · older people with age‐related memory loss
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Cognitive decline · older people with age‐related memory loss
1 finding from 1 review
Activities of daily living · older people with age‐related memory loss
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Health‐related quality of life · older people with age‐related memory loss
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Incidence of Alzheimer's disease · people with MCI
The intervention probably leads to higher incidence of Alzheimer's disease (moderate certainty).
1 finding from 1 review
Intervention not reported
Adverse events – cardiovascular · people with MCI
The intervention showed no clear difference in adverse events – cardiovascular (moderate certainty).
1 finding from 1 review
Intervention not reported
Adverse events – gastrointestinal · people with MCI
The intervention probably leads to higher adverse events – gastrointestinal (moderate certainty).
1 finding from 1 review
Intervention not reported
Mortality · people with MCI
The intervention showed no clear difference in mortality (moderate certainty).
1 finding from 1 review
Intervention not reported
Cognitive decline from baseline · people with MCI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Activities of daily living · people with MCI
1 finding from 1 review
Intervention not reported
Health‐related quality of life · people with MCI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Incidence of Alzheimer's disease · cognitively healthy people in late life
Other NSAIDs showed no clear difference in incidence of Alzheimer's disease compared with placebo (moderate certainty).
1 finding from 1 review
Adverse events: myocardial infarction · cognitively healthy people in late life
Other NSAIDs showed no clear difference in adverse events –myocardial infarction compared with placebo (moderate certainty).
1 finding from 1 review
Adverse effects ‐ Stroke · cognitively healthy people in late life
Other NSAIDs showed no clear difference in adverse events – stroke compared with placebo (moderate certainty).
1 finding from 1 review