Ipsilateral major or disabling stroke · asymptomatic carotid stenosis
Antiplatelet agent showed no clear difference in ipsilateral major or disabling stroke (CT scan or MRI) compared with placebo (low certainty).
1 finding from 1 review
Progression of carotid stenosis · asymptomatic carotid stenosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events (hospital records/every 6 weeks) · asymptomatic carotid stenosis
Lipid‐lowering agent showed no clear difference in adverse events (only reported for two studies: one study used CT… compared with placebo or no treatment (low certainty).
1 finding from 1 review
Quality of life · asymptomatic carotid stenosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Stroke‐related mortality · asymptomatic carotid stenosis
Antiplatelet agent showed no clear difference in stroke‐related mortality (CT scan or MRI) compared with placebo (low certainty).
1 finding from 1 review
Major bleeding · asymptomatic carotid stenosis
It is very uncertain whether antiplatelet agent changes major bleeding (not reported) compared with placebo (very low certainty).
1 finding from 1 review
Progression of carotid stenosis · asymptomatic carotid stenosis
Antiplatelet agent showed no clear difference in progression of carotid stenosis (DUS/every 6 months) compared with placebo (low certainty).
1 finding from 1 review
Adverse events (not reported) · asymptomatic carotid stenosis
Antiplatelet agent showed no clear difference in adverse events (not reported) compared with placebo (low certainty).
1 finding from 1 review
Quality of life · asymptomatic carotid stenosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Outcomes (measurement/time point) · asymptomatic carotid stenosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality at up to day 28 ‐ total · individuals with moderate to severe disease
Summary of findings table ‐ Convalescent plasma showed no clear difference in all‐cause mortality at up to day 28 ‐ total compared with placebo or standard care alone (high certainty).
1 finding from 1 review
All‐cause mortality at up to day 28 · outpatients withmild disease
It is very uncertain whether summary of findings table ‐ Convalescent plasma changes all‐cause mortality at up to day 28 compared with placebo or standard care alone (very low certainty).
1 finding from 1 review
Clinical worsening: need for invasive mechanical ventilation, or death at up to day 28 · individuals with moderate to severe disease
Summary of findings table ‐ Convalescent plasma showed no clear difference in clinical worsening: need for invasive mechanical ventilation, or… compared with placebo or standard care alone (high certainty).
1 finding from 1 review
Admission to hospital or death within 28 days · outpatients withmild disease
Summary of findings table ‐ Convalescent plasma showed no clear difference in admission to hospital or death within 28 days compared with placebo or standard care alone (low certainty).
1 finding from 1 review
Resolution of symptoms · outpatients withmild disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Time to symptom resolution · outpatients withmild disease
Summary of findings table ‐ Convalescent plasma showed no clear difference in time to symptom resolution (absolute effect calculated for day 12) compared with placebo or standard care alone (low certainty).
1 finding from 1 review
Quality of life, · outpatients withmild disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Grades 3 and 4 adverse events · outpatients withmild disease
Summary of findings table ‐ Convalescent plasma showed no clear difference in grades 3 and 4 adverse events compared with placebo or standard care alone (low certainty).
1 finding from 1 review
Serious adverse events · outpatients withmild disease
Summary of findings table ‐ Convalescent plasma showed no clear difference in serious adverse events compared with placebo or standard care alone (low certainty).
1 finding from 1 review
Clinical improvement: participants discharged from hospital ‐ not reported · individuals with moderate to severe disease
Summary of findings table ‐ Convalescent plasma showed no clear difference in clinical improvement: participants discharged from hospital compared with placebo or standard care alone (high certainty).
1 finding from 1 review