What do systematic reviews say?

Alglucosidase alfa plus albuterol vs alglucosidase alfa plus placebo

The review found no eligible studies for this question.

• Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Alglucosidase alfa plus albuterol vs alglucosidase alfa plus placebo

It is very uncertain whether alglucosidase alfa plus albuterol changes adverse events compared with alglucosidase alfa plus placebo (very low certainty).

• Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
  RR 0.67 [0.38, 1.18]
  1 study · 13 participants
  Very low

Cipaglucosidase plus miglustat vs alglucosidase alfa plus placebo

• Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 117 participants
  Low

Alglucosidase alfa vs placebo

Alglucosidase alfa showed no clear difference in infusion reactions compared with placebo (low certainty).

• Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
  RR 1.21 [0.57, 2.61]
  1 study · 90 participants
  Low

Cipaglucosidase plus miglustat vs alglucosidase alfa plus placebo

• Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 133 participants
  Moderate

Cipaglucosidase plus miglustat vs alglucosidase alfa plus placebo

• Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 121 participants
  Low

Cipaglucosidase plus miglustat vs alglucosidase alfa plus placebo

Cipaglucosidase plus miglustat showed no clear difference in infusion reactions compared with alglucosidase alfa plus placebo (low certainty).

• Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
  RR 0.94 [0.49, 1.8]
  1 study · 123 participants
  Low

Cipaglucosidase plus miglustat vs alglucosidase alfa plus placebo

The review found no eligible studies for this question.

• Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Cipaglucosidase plus miglustat vs alglucosidase alfa plus placebo

The review found no eligible studies for this question.

• Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Cipaglucosidase plus miglustat vs alglucosidase alfa plus placebo

• Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 121 participants
  Low

Cipaglucosidase plus miglustat vs alglucosidase alfa plus placebo

Cipaglucosidase plus miglustat showed no clear difference in treatment‐related AEs: total treatment‐emergent adverse events… compared with alglucosidase alfa plus placebo (low certainty).

• Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
  RR 0.83 [0.49, 1.4]
  1 study · 123 participants
  Low

Alglucosidase alfa vs placebo

The review found no eligible studies for this question.

• Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Alglucosidase alfa vs placebo

The review found no eligible studies for this question.

• Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Alglucosidase alfa vs placebo

• Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 90 participants
  Low

Alglucosidase alfa vs placebo

Alglucosidase alfa showed no clear difference in treatment‐related AEs compared with placebo (low certainty).

• Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
  RR 0.94 [0.64, 1.39]
  1 study · 90 participants
  Low

Alglucosidase alfa plus clenbuterol vs alglucosidase alfa plus placebo

• Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 10 participants
  Very low

Alglucosidase alfa plus clenbuterol vs alglucosidase alfa plus placebo

• Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 11 participants
  Very low

Aromatherapy vs placebo or usual care

The review found no eligible studies for this question.

• Interventions for fatigue in people with kidney failure requiring dialysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Aromatherapy vs placebo or usual care

The review found no eligible studies for this question.

• Interventions for fatigue in people with kidney failure requiring dialysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Aromatherapy vs placebo or usual care

The review found no eligible studies for this question.

• Interventions for fatigue in people with kidney failure requiring dialysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found