Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,730 questions · 18,059 findings · 1,282 reviews

No studies found 4,360 · 24.1%GRADE not reported 2,529 · 14%Very low 4,641 · 25.7%Low 4,007 · 22.2%Moderate 2,057 · 11.4%High 465 · 2.6%

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Intervention not reported

TXA given intravenously and intra‐articularly at a total dose of greater than 3 g pre‐incision, intraoperatively and postoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin) Comparator…
1 finding from 1 review

Intervention not reported

TXA given orally and intra‐articularly at a total dose of greater than 3 g pre‐incision, intraoperatively and postoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin) Comparator…
1 finding from 1 review