Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,256 questions · 2,339 findings · 262 reviews

No studies found 555 · 23.7%GRADE not reported 398 · 17%Very low 572 · 24.5%Low 476 · 20.4%Moderate 240 · 10.3%High 98 · 4.2%

Nitrous oxide vs carbon dioxide

Procedure‐related general complications · people undergoing laparoscopic general abdominal or gynaecological pelvic surgery under general anaesthesia

It is very uncertain whether nitrous oxide changes procedure‐related general complications (surgical morbidity) compared with carbon dioxide (very low certainty).

1 finding from 1 review

Room air vs carbon dioxide

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · people undergoing laparoscopic general abdominal or gynaecological pelvic surgery under general anaesthesia

It is very uncertain whether room air changes pain scores (first postoperative day) Visual analogue scale, lower… compared with carbon dioxide (very low certainty).

1 finding from 1 review

Nitrous oxide vs carbon dioxide

Participant‐reported pain intensity VAS (0‐10, lower score = less pain) · people undergoing laparoscopic general abdominal or gynaecological pelvic surgery under general anaesthesia

It is very uncertain whether nitrous oxide changes pain scores (first postoperative day) VAS, lower score indicates… compared with carbon dioxide (very low certainty).

1 finding from 1 review