Findings

What do systematic reviews say?

2,261 questions · 2,280 findings · 114 reviews · Cystic Fibrosis and Genetic Disorders

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No studies found 856 · 37.5%GRADE not reported 58 · 2.5%Very low 550 · 24.1%Low 502 · 22%Moderate 271 · 11.9%High 43 · 1.9%

Preoperative blood transfusion vs no transfusion

Serious complications related to SCD ‐ ACS · people with SCD

1 finding from 1 review

Preoperative blood transfusions for sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 434 participants
Very low

Silboesterol vs placebo

Detumescence · men and boys with SCD and stuttering priapism

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for priapism in boys and men with sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Sildenafil vs placebo

Effect on later sexual function · men and boys with SCD and stuttering priapism

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for priapism in boys and men with sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Sildenafil vs placebo

Other untoward side effects of treatment · men and boys with SCD and stuttering priapism

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for priapism in boys and men with sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Sildenafil vs placebo

Efficacy of a prevention strategy · men and boys with SCD and stuttering priapism

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for priapism in boys and men with sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Etilefrine vs placebo

Detumescence · men and boys with SCD and stuttering priapism

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for priapism in boys and men with sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Etilefrine vs placebo

Reduction in frequency of priapism · men and boys with SCD and stuttering priapism

1 finding from 1 review

Treatments for priapism in boys and men with sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 23 participants
Very low

Etilefrine vs placebo

Immediate side effects of treatment (palpitations) · men and boys with SCD and stuttering priapism

It is very uncertain whether etilefrine changes immediate side effects of treatment (palpitations) compared with placebo (very low certainty).

1 finding from 1 review

Treatments for priapism in boys and men with sickle cell disease 2020 · Cochrane Headline outcomes only
RR 1.64 [0.62, 4.3]
1 study · 23 participants
Very low

Etilefrine vs placebo

Immediate side effects of treatment (tachycardia) · men and boys with SCD and stuttering priapism

It is very uncertain whether etilefrine changes immediate side effects of treatment (tachycardia) compared with placebo (very low certainty).

1 finding from 1 review

Treatments for priapism in boys and men with sickle cell disease 2020 · Cochrane Headline outcomes only
RR 2.18 [0.71, 6.68]
1 study · 23 participants
Very low

Etilefrine vs placebo

Effect on later sexual function · men and boys with SCD and stuttering priapism

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for priapism in boys and men with sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Etilefrine vs placebo

Other untoward side effects of treatment · men and boys with SCD and stuttering priapism

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for priapism in boys and men with sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Etilefrine vs placebo

Efficacy of a prevention strategy · men and boys with SCD and stuttering priapism

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for priapism in boys and men with sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Silboesterol vs placebo

Reduction in stuttering priapism · men and boys with SCD and stuttering priapism

It is very uncertain whether silboesterol changes reduction in stuttering priapism compared with placebo (very low certainty).

1 finding from 1 review

Treatments for priapism in boys and men with sickle cell disease 2020 · Cochrane Headline outcomes only
RR 2.92 [0.73, 11.7]
1 study · 7 participants
Very low

Ephedrine vs placebo

Detumescence · men and boys with SCD and stuttering priapism

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for priapism in boys and men with sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Ephedrine vs placebo

Reduction in frequency of priapism · men and boys with SCD and stuttering priapism

1 finding from 1 review

Treatments for priapism in boys and men with sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 24 participants
Very low

Ephedrine vs placebo

Immediate side effects of treatment with 30 mg ephedrine (palpitations) · men and boys with SCD and stuttering priapism

It is very uncertain whether ephedrine changes immediate side effects of treatment with 30 mg ephedrine… compared with placebo (very low certainty).

1 finding from 1 review

Treatments for priapism in boys and men with sickle cell disease 2020 · Cochrane Headline outcomes only
RR 1 [0.32, 3.1]
1 study · 24 participants
Very low

Ephedrine vs placebo

Immediate side effects of treatment (tachycardia) · men and boys with SCD and stuttering priapism

It is very uncertain whether ephedrine changes immediate side effects of treatment with 30 mg ephedrine (tachycardia) compared with placebo (very low certainty).

1 finding from 1 review

Treatments for priapism in boys and men with sickle cell disease 2020 · Cochrane Headline outcomes only
RR 0.67 [0.13, 3.3]
1 study · 24 participants
Very low

Ephedrine vs placebo

Effect on later sexual function · men and boys with SCD and stuttering priapism

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for priapism in boys and men with sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Ephedrine vs placebo

Other untoward side effects of treatment · men and boys with SCD and stuttering priapism

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for priapism in boys and men with sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Ephedrine vs placebo

Efficacy of a prevention strategy · men and boys with SCD and stuttering priapism

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for priapism in boys and men with sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found