Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,411 questions · 5,986 findings · 226 reviews · Oral Health

No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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Powered toothbrushing (as part of comprehensive oral care) vs Manual toothbrushing

Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU

Powered toothbrushing (as part of comprehensive oral care) showed no clear difference in incidence of VAP compared with manual toothbrushing (standard oral care); GRADE not reported.

1 finding from 1 review

Audiovisual distraction vs Conventional treatment

Anxiety · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

Audiovisual distraction led to lower pre- and post-operative anxiety measures (Modified Child Dental… compared with conventional treatment; GRADE not reported.

1 finding from 1 review

Clinical examination with risk-based recall vs Clinical examination with 6-month recall

Cost (healthcare-system perspective): total cost per patient (GBP) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with risk-based recall showed no clear difference in cost (healthcare-system perspective): total cost per patient (GBP) compared with clinical examination with 6-month recall; GRADE not reported.

1 finding from 1 review

The wand (computer-controlled LA delivery system) vs other local anaesthetic

Successful LA/painless treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

All fluorescence-based devices (red, blue, and green fluorescence combined) vs Reference standard (histology, excavation, or enhanced visual examination)

Diagnostic odds ratio (DOR) for detection of early enamel caries (D1 threshold) · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review

Camouflage syringe vs Conventional syringe

Patient satisfaction: measured by questionnaires · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Hypnosis vs Conventional treatment

Adverse effects · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Moxifloxacin + SRP vs SRP

Clinical attachment level (CAL) · Adults with chronic periodontitis

Moxifloxacin + SRP led to lower clinical attachment level (CAL) compared with SRP; GRADE not reported.

2 findings from 1 review

High-volume evacuation (HVE) vs No HVE

Reduction in level of contamination in aerosols (CFU) at more than 1 foot from oral cavity (CCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting

High-volume evacuation (HVE) led to lower reduction in level of contamination in aerosols (CFU) at more than 1… compared with no HVE; GRADE not reported.

1 finding from 1 review

Audiovisual distraction vs Conventional treatment

Self- or observational assessment of intraoperative distress/pain/acceptance of treatment during provision of LA: pain-related behaviour during LA (negative vs positive behaviour; Frankl Behaviour Rating Scale) · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

It is very uncertain whether audiovisual distraction changes self- or observational assessment of intraoperative… compared with conventional treatment (very low certainty).

1 finding from 1 review

Clinical examination with risk-based recall vs Clinical examination with 6-month recall

Cost (patient perspective): total cost per patient (GBP) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with risk-based recall showed no clear difference in cost (patient perspective): total cost per patient (GBP) compared with clinical examination with 6-month recall; GRADE not reported.

1 finding from 1 review

Surgical removal (extraction) of asymptomatic disease-free impacted wisdom teeth vs Retention (conservative management) of asymptomatic disease-free impacted wisdom teeth

Other pathological changes associated with retention (pericoronitis, root resorption, cyst formation, tumour formation, inflammation/infection) · Adolescents or adults with asymptomatic disease-free impacted wisdom teeth

The review found no eligible studies for this question.

1 finding from 1 review

Cinnamon extract coolant vs Distilled water coolant

Reduction in level of contamination in aerosols (CFU): cinnamon extract coolant vs distilled water during ultrasonic scaling · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether cinnamon extract coolant changes reduction in level of contamination in aerosols (CFU): cinnamon… compared with distilled water coolant (very low certainty).

1 finding from 1 review

Clarithromycin + SRP vs SRP

Probing pocket depth · Adults with periodontitis (chronic and aggressive)

Clarithromycin + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.

2 findings from 1 review