Intervention not reported
Infection‐ related mortality
The intervention showed no clear difference in infection‐ related mortality (low certainty).
1 finding from 1 review
Intervention not reported
Second cancer‐ related mortality
The intervention showed no clear difference in second cancer‐ related mortality (low certainty).
1 finding from 1 review
Intervention not reported
Cardiac disease‐ related mortality
The intervention showed no clear difference in cardiac disease‐ related mortality (low certainty).
1 finding from 1 review
Intervention not reported
Complete response rate
The intervention showed no clear difference in complete response rate (low certainty).
1 finding from 1 review
Intervention not reported
Mortality (calculated instead of overall survival)
The intervention may leads to higher mortality (calculated instead of overall survival) (low certainty).
1 finding from 1 review
Intervention not reported
Relapse, progression or death (calculated instead of PFS)
The intervention showed no clear difference in relapse, progression or death (calculated instead of PFS) (low certainty).
1 finding from 1 review
Intervention not reported
Incidence of GTN (including low‐quality studies) · women with a molar pregnancy
The intervention may leads to lower incidence of GTN (including low‐quality studies) (low certainty).
1 finding from 1 review
Intervention not reported
Incidence of GTN (excluding low‐quality studies) · women with a molar pregnancy
The intervention may leads to lower incidence of GTN (excluding low‐quality studies) (low certainty).
1 finding from 1 review
Intervention not reported
Time to GTN diagnosis (days) · women with a molar pregnancy
The intervention may leads to higher time to GTN diagnosis (days) (low certainty).
1 finding from 1 review
Intervention not reported
Overall survival · people with non‐rhabdomyosarcoma soft tissue sarcoma
The intervention showed no clear difference in overall survival (high certainty).
1 finding from 1 review
Intervention not reported
Treatment‐related mortality · people with non‐rhabdomyosarcoma soft tissue sarcoma
1 finding from 1 review
Intervention not reported
Disease‐free survival · people with non‐rhabdomyosarcoma soft tissue sarcoma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Progression‐free survival · people with non‐rhabdomyosarcoma soft tissue sarcoma
The intervention showed no clear difference in progression‐free survival (high certainty).
1 finding from 1 review
Intervention not reported
Non‐hematologic toxicity grade 3 to 4 · people with non‐rhabdomyosarcoma soft tissue sarcoma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Health‐related quality of life · people with non‐rhabdomyosarcoma soft tissue sarcoma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Overall survival · Women with newly diagnosed epithelial ovarian cancer
The intervention leads to lower overall survival (high certainty).
1 finding from 1 review
Intervention not reported
hearing loss · Women with newly diagnosed epithelial ovarian cancer
The intervention leads to lower hearing loss (high certainty).
1 finding from 1 review
Intervention not reported
Progression‐free survival · Women with newly diagnosed epithelial ovarian cancer
The intervention leads to lower progression‐free survival (high certainty).
1 finding from 1 review
Intervention not reported
Severe adverse effects (G3/4) outcomes · Women with newly diagnosed epithelial ovarian cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
fever · Women with newly diagnosed epithelial ovarian cancer
The intervention leads to higher fever (high certainty).
1 finding from 1 review