Misoprostol vs expectant care
Misoprostol showed no clear difference in unplanned surgical intervention compared with expectant care (low certainty).
- RR 0.62 [0.17, 2.26]2 studies · 308 participantsLow
Misoprostol showed no clear difference in unplanned surgical intervention compared with expectant care (low certainty).
It is very uncertain whether misoprostol changes complete miscarriage compared with surgery (very low certainty).
It is very uncertain whether misoprostol changes surgical evacuation compared with surgery (very low certainty).
Potassium citrate may leads to lower proportion of participants who developed a new urinary stone compared with no intervention (low certainty).
It is very uncertain whether potassium citrate changes proportion of participants with adverse events while undergoing… compared with no intervention (very low certainty).
The review found no eligible studies for this question.
Surgery probably leads to higher control of bleeding (cure or improvement to acceptable level) At 4… compared with oral medication (moderate certainty).
Surgery showed no clear difference in satisfaction rate: surgery versus LNG‐IUS Endometrial ablation… compared with LNG‐IUS (low certainty).
Surgery probably leads to lower proportion of women with adverse events Endometrial ablation versus… compared with LNG‐IUS (moderate certainty).
Surgery probably leads to higher overall satisfaction with treatment At 2 years compared with oral medication (moderate certainty).
It is very uncertain whether surgery changes overall satisfaction with treatment At 5 years compared with oral medication (very low certainty).
Surgery probably leads to lower adverse events at 4 months compared with oral medication (moderate certainty).
Surgery probably leads to higher objective control of bleeding: menstrual loss under 80 ml per cycle… compared with LNG‐IUS (moderate certainty).
Surgery may leads to higher subjective control of bleeding: PBAC no more than 75 per cycle… compared with LNG‐IUS (low certainty).
Surgery showed no clear difference in satisfaction rate: surgery versus LNG‐IUS Endometrial ablation… compared with LNG‐IUS (low certainty).
Summary of findings for imiquimod leads to higher response to treatment at 5 to 6 months ‐ overall response compared with placebo (high certainty).