Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,447 questions · 2,590 findings · 266 reviews

No studies found 699 · 27%GRADE not reported 289 · 11.2%Very low 614 · 23.7%Low 605 · 23.4%Moderate 322 · 12.4%High 61 · 2.4%

Pregabalin vs active comparators

50% or greater reduction in seizure frequency · people with drug‐resistant focal epilepsy

Pregabalin showed no clear difference in 50% or greater reduction in seizurefrequency compared with active comparators (low certainty).

3 findings from 1 review