Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,822 questions · 1,891 findings · 321 reviews · Headline outcomes only

No studies found 279 · 14.8%GRADE not reported 46 · 2.4%Very low 524 · 27.7%Low 571 · 30.2%Moderate 330 · 17.5%High 141 · 7.5%

Higher polyunsaturated fatty acid (PUFA) vs lower PUFA

Major adverse cardiac and cerebrovascular events · people with or without existing CVD, men and women

It is very uncertain whether higher polyunsaturated fatty acid (PUFA) changes major adverse cardiac and cerebrovascular events compared with lower PUFA (very low certainty).

1 finding from 1 review

Higher polyunsaturated fatty acid (PUFA) vs lower PUFA

Cardiovascular events · people with or without existing cardiovascular disease, men and women

Higher polyunsaturated fatty acid (PUFA) showed no clear difference in cardiovascular events compared with lower PUFA (moderate certainty).

1 finding from 1 review

Higher polyunsaturated fatty acid (PUFA) vs lower PUFA

Coronary heart disease mortality – CHD deaths · people with or without existing cardiovascular disease, men and women

Higher polyunsaturated fatty acid (PUFA) showed no clear difference in coronary heart disease mortality compared with lower PUFA (low certainty).

1 finding from 1 review

Higher polyunsaturated fatty acid (PUFA) vs lower PUFA

Atrial fibrillation and arrhythmias · people with or without existing cardiovascular disease, men and women

It is very uncertain whether higher polyunsaturated fatty acid (PUFA) changes atrial fibrillation and arrhythmias compared with lower PUFA (very low certainty).

1 finding from 1 review

Summary of findings: Higher bladder volume vs lower bladder volume

Acute and late GI toxicity (grade 2+) · Men undergoing RT for prostate cancer

Summary of findings: Higher bladder volume showed no clear difference in acute and late GI toxicity (grade 2+) compared with lower bladder volume (low certainty).

1 finding from 1 review