Findings

What do systematic reviews say?

1,835 questions · 1,886 findings · 74 reviews · Skin

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No studies found 542 · 28.7%GRADE not reported 130 · 6.9%Very low 326 · 17.3%Low 434 · 23%Moderate 348 · 18.5%High 106 · 5.6%

Low‐level laser comb vs Placebo (sham/placebo device)

Change in quality of life ‐ not measured · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Low‐level laser comb vs Placebo (sham/placebo device)

Adverse events · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 141 participants
Low

Low‐level laser comb vs Placebo (sham/placebo device)

Participants with investigator‐rated clinically significant hair regrowth ‐ not measured · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Low‐level laser comb vs Placebo (sham/placebo device)

Change from baseline to study conclusion in total hair count · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 122 participants
Low

Minoxidil vs placebo

Adverse events · women with FPHL

Minoxidil showed no clear difference in adverse events compared with placebo (low certainty).

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
RR 1.24 [0.82, 1.87]
4 studies · 727 participants
Low

Low‐level laser comb vs Placebo (sham/placebo device)

Degree of hair shedding from baseline to the end of the study · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Low‐level laser comb vs Placebo (sham/placebo device)

Cosmetic appearance of the hair or participant satisfaction · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 141 participants
Moderate

Low‐level laser comb vs Placebo (sham/placebo device)

Change in quality (or pattern) of hair regrowth (e.g. thickness) ‐ not measured · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Minoxidil vs placebo

Proportion of participants with investigator‐rated clinically significant hair regrowth · women with FPHL

Minoxidil probably leads to higher proportion of participants with investigator‐rated clinically… compared with placebo (moderate certainty).

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
RR 2.35 [1.68, 3.28]
7 studies · 1181 participants
Moderate

Minoxidil vs placebo

Change from baseline to study conclusion in total hair count · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1242 participants
Low

Minoxidil vs placebo

Degree of hair shedding from baseline to the end of the study · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 380 participants
Very low

Minoxidil vs placebo

Cosmetic appearance of the hair or participant satisfaction · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 260 participants
Low

Minoxidil vs placebo

Change in quality (or pattern) of hair regrowth (e.g. thickness) · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 372 participants
Low

Minoxidil 2% vs minoxidil 5%

Proportion of participants with self‐rated clinically significant hair regrowth · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 322 participants
Low

Light therapies (including photodynamic therapy) vs placebo, no treatment, topical treatment and other comparators

Participant's global assessment of improvement Non‐standardised scale5 · Mild, moderate and severe acne vulgaris

1 finding from 1 review

Light therapies for acne 2016 · Cochrane Headline outcomes only
no estimate extracted
23 studies · 1033 participants
Very low

MAL‐PDT vs red light only

Investigator's global assessment (IGA) of improvement Treatment 'success' as defined by IGA score decrease5 · Moderate and severe acne vulgaris

MAL‐PDT probably leads to higher investigator's global assessment (IGA) of improvement Treatment… compared with red light only (moderate certainty).

1 finding from 1 review

Light therapies for acne 2016 · Cochrane Headline outcomes only
RR 1.74 [1.11, 2.74]
3 studies · 360 participants
Moderate

ALA‐PDT vs blue light only

Participant's global assessment of improvement Non‐standardised scale5 · Moderate and severe acne vulgaris

ALA‐PDT showed no clear difference in participant's global assessment of improvement Non‐standardised scale5 compared with blue light only (low certainty).

1 finding from 1 review

Light therapies for acne 2016 · Cochrane Headline outcomes only
RR 0.87 [0.72, 1.04]
1 study · 266 participants
Low

ALA‐PDT vs blue light only

Investigator‐assessed change in inflamed lesions (ILs) Lesion counts · Moderate and severe acne vulgaris

1 finding from 1 review

Light therapies for acne 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 266 participants
Very low

ALA‐PDT vs blue light only

Investigator‐assessed percentage change in ILs Lesion counts · Moderate and severe acne vulgaris

1 finding from 1 review

Light therapies for acne 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 266 participants
Very low

ALA‐PDT vs blue light only

Investigator‐assessed severe adverse effects Application site blister · Moderate and severe acne vulgaris

1 finding from 1 review

Light therapies for acne 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 266 participants
Very low