Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,734 questions · 15,288 findings · 893 reviews

No studies found 3,864 · 25.3%GRADE not reported 2,222 · 14.5%Very low 3,868 · 25.3%Low 3,280 · 21.5%Moderate 1,676 · 11%High 378 · 2.5%

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Intervention not reported

All intervention options · people with first recurrence of glioblastoma Interventions: bevacizumab (BEV), BEV + lomustine (LOM), regorafenib (REG), fotemustine…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

BEV+IRI (1 RCT, 79 participants) · people with any recurrence of glioblastoma Interventions: bevacizumab (BEV) Comparison: bevacizumab 9BEV), BEV+carboplatin (CAB),…

The intervention leads to higher BEV+IRI (1 RCT, 79 participants) (high certainty).

1 finding from 1 review

Intervention not reported

BEV+VB111 (1 RCT, 128 participants) · people with any recurrence of glioblastoma Interventions: bevacizumab (BEV) Comparison: bevacizumab 9BEV), BEV+carboplatin (CAB),…

The intervention leads to higher BEV+VB111 (1 RCT, 128 participants) (high certainty).

1 finding from 1 review

Intervention not reported

BEV+TRC 105 (1 RCT, 49 participants) · people with any recurrence of glioblastoma Interventions: bevacizumab (BEV) Comparison: bevacizumab 9BEV), BEV+carboplatin (CAB),…

The intervention leads to higher BEV+TRC 105 (1 RCT, 49 participants) (high certainty).

1 finding from 1 review

Intervention not reported

All intervention options · people with first recurrence of glioblastoma Interventions: bevacizumab (BEV), BEV + lomustine (LOM), regorafenib (REG), BEV + irinotecan…

The review found no eligible studies for this question.

1 finding from 1 review