Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,097 questions · 3,266 findings · 631 reviews

No studies found 430 · 13.2%GRADE not reported 193 · 5.9%Very low 995 · 30.5%Low 904 · 27.7%Moderate 591 · 18.1%High 153 · 4.7%

Impulsive lifestyle counselling + treatment‐as‐usual vs usual care

Aggression: trait Assessed by: Buss‐Perry Aggression Questionnaire ‐ Short Form (12 items rated on 5‐point Likert scale ranging from extremely uncharacteristic (1) to extremely characteristic (5); range = 12‐60; high score = poor outcome) Timing o... · adults with antisocial personality disorder
1 finding from 1 review

Intervention not reported

Adverse events ‐ Ectopic pregnancy Melatonin lower dose versus melatonin higher dose№ of participants: 120(1 RCT) · women with subfertility
1 finding from 1 review

Intervention not reported

Live birth; type of antioxidant (natural conceptions and undergoing fertility treatments) ‐ Melatonin lower dose versus melatonin higher dose№ of participants: 140(2 RCTs) · women with subfertility

The intervention showed no clear difference in live birth; type of antioxidant (natural conceptions and undergoing… (low certainty).

1 finding from 1 review

Intervention not reported

Clinical pregnancy; type of antioxidant (natural conceptions and undergoing fertility treatments) ‐ Melatonin lower dose versus melatonin higher dose№ of participants: 140(2 RCTs) · women with subfertility

The intervention showed no clear difference in clinical pregnancy; type of antioxidant (natural conceptions and… (low certainty).

1 finding from 1 review

LNG‐IUS vs oral progestogen (norethisterone acetate)

Change in haemoglobin level from baseline · women with uterine fibroids
2 findings from 1 review

Therapeutic ultrasound vs placebo

Pain intensity VAS (0 to 100; 0 = no pain, 100 = worst pain) · adults with chronic low‐back pain

It is very uncertain whether therapeutic ultrasound changes pain intensity Scale: VAS (100‐point scale; higher scores mean… compared with placebo (very low certainty).

1 finding from 1 review

Therapeutic ultrasound plus exercise vs exercise

Well‐being Scale: general health subscale of SF‐36 (higher scores mean worse well‐being) · adults with chronic low‐back pain

It is very uncertain whether therapeutic ultrasound plus exercise changes well‐being Scale: general health subscale of SF‐36 (higher scores… compared with exercise alone (very low certainty).

1 finding from 1 review

Therapeutic ultrasound vs placebo

Back‐specific functional status · adults with chronic low‐back pain

Therapeutic ultrasound showed no clear difference in back‐specific functional status Scale: Functional Rating Index,… compared with placebo (low certainty).

1 finding from 1 review

Therapeutic ultrasound vs placebo

Well‐being Scale: general health subscale of SF‐36 (higher scores mean worse well‐being) · adults with chronic low‐back pain

Therapeutic ultrasound showed no clear difference in well‐being Scale: general health subscale of SF‐36 (higher scores… compared with placebo (moderate certainty).

1 finding from 1 review

Therapeutic ultrasound plus exercise vs exercise

Pain intensity VAS (0 to 100; 0 = no pain, 100 = worst pain) · adults with chronic low‐back pain

It is very uncertain whether therapeutic ultrasound plus exercise changes pain intensity Scale: VAS (100‐point scale; higher scores mean… compared with exercise alone (very low certainty).

1 finding from 1 review

Carboplatin vs cisplatin chemotherapy

Overall survival (baseline risks for low‐ and high‐risk groups in the control arm were estimated at 1 year) · combination with third‐generation drugs for advanced non‐small cell lung cancer

Carboplatin showed no clear difference in overall survival (baseline risks for low‐ and high‐risk groups in… compared with cisplatin chemotherapy (high certainty).

1 finding from 1 review